Browsing Ciències Bàsiques by Issue Date
Now showing items 41-60 of 65
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Assessing the potential role of copper and cobalt in stimulating angiogenesis for tissue regeneration
(PLoS One, 2021)The use of copper (Cu2+) and cobalt (Co2+) has been described to stimulate blood vessel formation, a key process for the success of tissue regeneration. However, understanding how different concentrations ... -
Multiple ion scaffold-based delivery platform for potential application in early stages of bone regeneration
(Materials, 2021)Bone has the intrinsic capacity to regenerate itself, as long as the damage is small, through the sequential stimulation of specific phases, such as angiogenesis followed by osteogenesis. However, when ... -
Dissociation of functional and structural plasticity of dendritic spines during NMDAR and mGluR-dependent long-term synaptic depression in wild-type and fragile X model mice
(Molecular Psychiatry, 2021)Many neurodevelopmental disorders are characterized by impaired functional synaptic plasticity and abnormal dendritic spine morphology, but little is known about how these are related. Previous work in ... -
Engineering a genome-reduced bacterium to eliminate Staphylococcus aureus biofilms in vivo
(Molecular Systems Biology, 2021)Bacteria present a promising delivery system for treating human diseases. Here, we engineered the genome-reduced human lung pathogen Mycoplasma pneumoniae as a live biotherapeutic to treat biofilm-associated ... -
Engineering a genome reduced bacterium to eliminate Staphylococcus aureus biofilms in vivo
(Molecular Systems Biology, 2021)Bacteria present a promising delivery system for treating human diseases. Here, we engineered the genome-reduced human lung pathogen Mycoplasma pneumoniae as a live biotherapeutic to treat biofilm-associated ... -
Structural characterization of NORAD reveals a stabilizing role of spacers and two new repeat units
(Computational and Structural Biotechnology Journal, 2021)Long non-coding RNAs (lncRNAs) can perform a variety of key cellular functions by interacting with proteins and other RNAs. Recent studies have shown that the functions of lncRNAS are largely mediated ... -
Maturation of biomimetic hydroxyapatite in physiological fluids: a physicochemical and proteomic study
(Materials Today Bio, 2021-09)Biomimetic calcium-deficient hydroxyapatite (CDHA) as a bioactive material exhibits exceptional intrinsic osteoinductive and osteogenic properties because of its nanostructure and composition, which ... -
Interexaminer reliability and validity of quantity of cervical mobility during online dynamic inspection
(Diagnostics, 2022)Background: Physical therapists routinely measure range of motion (ROM) of cervical spine. The reliability of the cervical range of motion (CROM) device has been demonstrated in several studies, but ... -
Correlation between physical performance and stabilometric parameters in older adults
(Medicina, 2022)Background and Objectives: Falls are a common and serious threat to the health and independence of older adults. The decrease in functional capacity during aging means an increased risk of falls. To ... -
SURE editing: combining oligo-recombineering and programmable insertion/deletion of selection markers to efficiently edit the Mycoplasma pneumoniae genome
(Nucleic Acids Research, 2022)The development of advanced genetic tools is boosting microbial engineering which can potentially tackle wide-ranging challenges currently faced by our society. Here we present SURE editing, a ... -
Global signalling network analysis of luminal T47D breast cancer cells in response to progesterone
(Frontiers in Endocrinology, 2022)Background: Breast cancer cells enter into the cell cycle following progestin exposure by the activation of signalling cascades involving a plethora of enzymes, transcription factors and co-factors that ... -
Influence of bone-level dental implants placement and of cortical thickness on osseointegration: in silico and in vivo analyses
(Journal of Clinical Medicine, 2022)The purpose of this research is to study the biomechanical response of dental implants in bone-level type locations, 0.5 mm above and below the bone level. In addition, the influence of the thickness ... -
Application of percutaneous needle electrolysis does not elicit temperature changes: an in vitro cadaveric study
(International Journal of Environmental Reseacrh and Public Health, 2022)Percutaneous needle electrolysis (PNE) consists of the ultrasound-guided application of a galvanic electrical current through a solid filament needle. One proposed therapeutic mechanism for this ... -
PhylomeDB V5: an expanding repository for genome-wide catalogues of annotated gene phylogenies
(Nucleic Acids Research, 2022)PhylomeDB is a unique knowledge base providing public access to minable and browsable catalogues of pre-computed genome-wide collections of annotated sequences, alignments and phylogenies (i.e. phylomes) ... -
The ADP-ribose hydrolase NUDT5 is important for DNA repair
(Cell Reports, 2022-12)DNA damage leads to rapid synthesis of poly(ADP-ribose) (pADPr), which is important for damage signaling and repair. pADPr chains are removed by poly(ADP-ribose) glycohydrolase (PARG), releasing free ... -
Study on balance and postural control sccording to the stabilometry in indoor skydivers: a cross-sectional study
(International Journal of Environmental Research and Public Health, 2023)Background: The wind tunnel is a compression cabin through which a stream of air rises homogeneously, generated by fans. To perform different acrobatics, indoor skydivers have to change their body ... -
Effectiveness of a multicomponent training program on physical performance and muscle quality in older adults: a quasi-experimental study
(International Journal of Environmental Research and Public Health, 2023)Aging is associated with a decrease in functional capacity, manifested by a loss of strength, physical performance and muscle quality. Multicomponent training (MCT), characterized by the combination of ... -
Engineered live bacteria suppress Pseudomonas aeruginosa infection in mouse lung and dissolve endotracheal-tube biofilms
(Nature Biotechnology, 2023)Engineered live bacteria could provide a new modality for treating lung infections, a major cause of mortality worldwide. In the present study, we engineered a genome-reduced human lung bacterium, ... -
Skull fractures by glass bottles tested on cadaveric heads
(International Journal of Legal Medicine, 2023)Head trauma is frequently related to the misuse of drinking vessels as weapons. Forensic reports usually evaluate these blunt injuries as having occurred in scenarios where the alcohol intake is high. ... -
The plant noncoding transcriptome: a versatile environmental sensor
(The EMBO Journal, 2023)Plant noncoding RNA transcripts have gained increasing attention in recent years due to growing evidence that they can regulate developmental plasticity. In this review article, we comprehensively analyze ...