Ciències de la Salut: Enviaments recents
Ara mostrant els elements 861-880 de 979
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Structural (betaalpha) 8 TIM barrel model of 3-hydroxy-3-methylglutaryl-coenzyme A lyase
(Journal of Biological Chemistry, 2003)This study describes three novel homozygous missense mutations (S75R, S201Y, and D204N) in the 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) lyase gene, which caused 3-hydroxy-3-methylglutaric aciduria in ... -
Hypothalamic AMPK-ER Stress-JNK1 axis mediates the central actions of thyroid hormones on energy balance
(Cell Metabolism, 2017-07)Thyroid hormones (THs) act in the brain to modulate energy balance. We show that central triiodothyronine (T3) regulates de novo lipogenesis in liver and lipid oxidation in brown adipose tissue (BAT) ... -
Socio-environmental correlates of physical activity in patients with chronic obstructive pulmonary disease (COPD)
(Thorax, 2017)Background. Study of the causes of the reduced levels of physical activity in patients with COPD has been scarce and limited to biological factors. Aim: To assess the relationship between novel ... -
Study on the use of 3‐aminopropyltriethoxysilane and 3‐chloropropyltriethoxysilane to surface biochemical modification of a novel low elastic modulus Ti–Nb–Hf alloy
(Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2014-06-09)A biocompatible new titanium alloy Ti–16Hf–25Nb with low elastic modulus (45 GPa) and the use of short bioadhesive peptides derived from the extracellular matrix have been studied. In terms of cell ... -
Surface immobilization and bioactivity of TGF-ß1 inhibitor peptides for bone implant applications
(Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2016-02-01)TGF-ß1 is the most related cytokine with the production of fibrotic tissue. It plays an important role on the production of collagen by fibroblasts and other types of cells. The inhibition of this ... -
Mechanical and microstructural characterization of new nickel-free low modulus beta-type titanium wires during thermomechanical treatments
(Materials Science and Engineering: A, 2015-06-11)NiTi alloy is the only practical shape memory alloy (SMA) in biomedical use because of its excellent mechanical stability and functionality. However, it is estimated that between 4.5% and 28.5% of the ... -
Surface guidance of stem cell behavior: chemically tailored co-presentation of integrin-binding peptides stimulates osteogenic differentiation in vitro and bone formation in vivo
(Acta Biomaterialia, 2016-10-01)Surface modification stands out as a versatile technique to create instructive biomaterials that are able to actively direct stem cell fate. Chemical functionalization of titanium has been used in this ... -
Silver deposition on titanium surface by electrochemical anodizing process reduces bacterial adhesion of Streptococcus sanguinis and Lactobacillus salivarius
(Clinical Oral Implants Research, 2014-05-30)Objectives: The aim of this study was to determine the antibacterial properties of silver‐doped titanium surfaces prepared with a novel electrochemical anodizing process. Material and methods: Titanium ... -
Mechanical and physicochemical characterization along with biological interactions of a new Ti25Nb21Hf alloy for bone tissue engineering
(Journal of Biomaterials Applications, 2015-03-23)Nowadays, one of the main challenges in metal implants for bone substitution is the achievement of an elastic modulus close to that of human cortical bone as well as to provide an adequate interaction ... -
Determination of fluid leakages in the different screw-retained implant-abutment connections in a mechanical artificial mouth
(Journal of Materials Science: Materials in Medicine, 2015-07-15)This study shows the potential risk of microfiltration between two different types of implant-abutment connections screwed at 45 Ncm: external and internal. For the first time the use of a mechanical ... -
Impedimetric antimicrobial peptide-based sensor for the early detection of periodontopathogenic bacteria
(Biosensors and Bioelectronics, 2016-12-15)Peri-implantitis, an inflammation caused by biofilm formation, constitutes a major cause of implant failure in dentistry. Thus, the detection of bacteria at the early steps of biofilm growth represents ... -
Development of tantalum scaffold for orthopaedic applications produced by space-holder method
(Materials & Design, 2015-10-15)In the present study, production of tantalum porous scaffolds using the space holder technique was performed. The effect of size and content of sodium chloride particles, used as space holder, as well ... -
Antibiotic-loaded polypropylene surgical meshes with suitable biological behaviour by plasma functionalization and polymerization
(Biomaterials, 2015-12)Hernia repair is one of the most common operations in general surgery, and its associated complications typically relate to infections, among others. The loading of antibiotics to surgical meshes to ... -
Revisiting the appropriation of space in metropolitan river corridors
(Journal of Environmental Psychology, 2015)This article reintroduces the concept of 'appropriation of space' into current theoretical debates and empirical approaches in environmental psychology. We present an analysis of a case study conducted ... -
Mi visita a la enfermería fenomenológica
(Investigaciones Fenomenológicas, 2018) -
Effects of sedatives and opioids on trigger and cycling asynchronies throughout mechanical ventilation: an observational study in a large dataset from critically ill patients
(Critical Care, 2019-07-05)Background: In critically ill patients, poor patient-ventilator interaction may worsen outcomes. Although sedatives are often administered to improve comfort and facilitate ventilation, they can be ... -
Evaluación de la aplicación de un protocolo de cribado nutricional en pacientes ingresados en el Servicio de Medicina de un hospital comarcal
(Nutrición Hospitalaria, 2020)Antecedentes: las técnicas de cribado e intervención nutricional en pacientes hospitalizados son una medida coste-efectiva. En la práctica clínica, el problema radica en cómo aplicarlas. Objetivo: evaluar ... -
Red blood cell distribution width as a prognostic factor of mortality in elderly patients firstly hospitalized due to heart failure
(Kardiologia Polska, 2019-04-29)Background: Red blood cell distribution width (RDW) is a risk factor related to adverse outcome in patients with heart failure (HF). Less is known about its role in patients in their first hospitalization ... -
Ozenoxacin, a new effective and safe topical treatment for impetigo in children and adolescents
(Dermatology, 2020)Background: Ozenoxacin is a topical antibiotic approved in Europe to treat non-bullous impetigo in adults and children aged ≥6 months. This analysis evaluated the efficacy and safety of ozenoxacin in ...