Evaluation of bone loss in antibacterial coated dental implants: an experimental study in dogs
Author
Godoy Gallardo, Maria
Manzanares-Céspedes, Maria Cristina
Sevilla Sánchez, Pablo
Nart Molina, José
Manzanares, Norberto
Manero Planella, José María
Gil Mur, Francisco Javier
Boyd, Steven K.
Rodríguez, Daniel
Publication date
2016-12ISSN
0928-4931
Abstract
The aim of this study was to evaluate the in vivo effect of antibacterial modified dental implants in the first stages of peri-implantitis. Thirty dental implants were inserted in the mandibular premolar sites of 5 beagle dogs. Sites were randomly assigned to Ti (untreated implants, 10 units), Ti_Ag (silver electrodeposition treatment, 10 units), and Ti_TSP (silanization treatment, 10 units). Coated implants were characterized by scanning electron microscopy, interferometry and X-ray photoelectron spectroscopy. Two months after implant insertion, experimental peri-implantitis was initiated by ligature placement. Ligatures were removed 2 months later, and plaque formation was allowed for 2 additional months. Clinical and radiographic analyses were performed during the study. Implant-tissue samples were prepared for micro computed tomography, backscattered scanning electron microscopy, histomorphometric and histological analyses and ion release measurements. X-ray, SEM and histology images showed that vertical bone resorption in treated implants was lower than in the control group (P < 0.05). This effect is likely due to the capacity of the treatments to reduce bacteria colonization on the implant surface. Histological analysis suggested an increase of peri-implant bone formation on silanized implants. However, the short post-ligature period was not enough to detect differences in clinical parameters among implant groups. Within the limits of this study, antibacterial surface treatments have a positive effect against bone resorption induced by peri-implantitis.
Document Type
Article
Document version
Accepted version
Language
English
Subject (CDU)
616.3 - Pathology of the digestive system. Complaints of the alimentary canal
Keywords
Implants dentals
Gossos
Bacteris
Implantes dentales
Perros
Bacterias
Dental implants
Dogs
Bacteria
Pages
31
Publisher
Elsevier
Collection
69;
Is part of
Materials Science and Engineering: C
Citation
Godoy-Gallardo, Maria; Manzanares-Céspedes, Maria Cristina; Sevilla, Pablo [et al.]. Evaluation of bone loss in antibacterial coated dental implants: an experimental study in dogs. Materials Science and Engineering: C, 2016, 69, p. 538-545. Disponible en: <https://www.sciencedirect.com/science/article/abs/pii/S0928493116306944?via%3Dihub>. Fecha de acceso: 28 jun. 2020. DOI: 10.1016/j.msec.2016.07.020
Grant agreement number
info:eu-repo/grantAgreement/ES/1PE/MAT2009-12547
info:eu-repo/grantAgreement/MINECO/6PN/MAT2012-30706
This item appears in the following Collection(s)
- Ciències de la Salut [725]
Rights
© 2016 Elsevier B.V. All rights reserved.