Why methylene blue should be blacklisted in neonatology

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Author
Silecchia, Valeria
Valerio, Enrico
Merazzi, Daniele
Iantorno, Lorenzo
Laguardia, Maria Chiara
Cutrone, Mario
Grimalt Santacana, Ramon
Publication date
2019
URI http://hdl.handle.net/20.500.12328/1601
DOI
http://dx.doi.org/10.17554/j.issn.2412-2424.2019.05.46-5
ISSN
2412-2424
Abstract
We here present a case of neonatal skin damage due to application of methylene blue (MB) on a newborn's skin. MB use should be completely eliminated in neonatal intensive care units and nurseries, because of three potentially dangerous adverse effects of this compound: (1) It may act as an irritant when applied topically on intact skin, leading to skin reddening up to deep full-thickness eschars; (2) Is possesses photosensitizing properties, and may produce skin reddening followed by blisters and peeling after UV phototherapy; (3) It is a proscribed substance in patients affected by glucose-6-phosphate dehydrogenase deficiency, a condition not easily detected in the very first days of life.
Document Type
Article
Document version
Accepted version
Language
English
Subject (CDU)
61 - Medicina
Keywords
Neonatologia
Dermatologia
Pediatria intensiva
Neonatología
Dermatología
Cuidados intensivos neonatales
Neonatology
Dermatology
Intensive care, neonatal
Pages
2
Publisher
ACT Publishing Group Limited
Collection
5;1
Is part of
Journal of Respiratory Research
Citation
Silecchia, Valeria; Valerio, Enrico; Merazzi, Daniele [et al.]. Why methylene blue should be blacklisted in neonatology. Journal of Respiratory Research, 2019. 5(1), p. 1-2. Disponible en: <http://www.ghrnet.org/index.php/jdr/article/view/2731/3037>. Fecha de acceso: 23 jun. 2020. DOI:10.17554/j.issn.2412-2424.2019.05.46-5
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© 2018 The Author(s). Published by ACT Publishing Group Ltd. All rights reserved. This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work noncommercially, and license their derivative works on different terms, provided the original work is properly cited and the use is noncommercial. See: http://creativecommons.org/licenses/by-nc/4.0/

© 2018 The Author(s). Published by ACT Publishing Group Ltd. All rights reserved. This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work noncommercially, and license their derivative works on different terms, provided the original work is properly cited and the use is noncommercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by-nc/4.0/