Installing multifunctionality on titanium with RGD-decorated polyurethane-polyurea roxithromycin loaded nanoparticles: toward new osseointegrative therapies
Author
Rocas, Pau
Hoyos Nogués, Mireia
Rocas, Josep
Manero Planella, José María
Gil Mur, Francisco Javier
Albericio Palomera, Fernando
Mas Moruno, Carlos
Publication date
2015ISSN
2192-2640
Abstract
A novel class of polyurethane-polyurea nanoparticles (PUUa NPs) to install multifunctionality on biomaterials is presented. Biofunctionalization of titanium with roxithromycin loaded RGD-decorated PUUa NPs results in an outstanding improvement of osteoblast adhesion and strong suppression of bacterial attachment. This strategy represents a powerful approach to enhance the osseointegration of implant materials.
Document Type
Article
Document version
Accepted version
Language
English
Subject (CDU)
61 - Medical sciences
Keywords
Titani
Materials biomèdics
Implants
Materials nanoestructurats
Pèptids
Titanio
Materiales biomédicos
Implantes
Materiales nanoestructurados
Péptidos
Titanium
Biomedical materials
Implants
Nanostructured materials
Peptides
Pages
5
Publisher
Wiley
Collection
4; 13
Is part of
Advanced Healthcare Materials
Citation
Rocas, Pau; Hoyos Nogués, Mireia; Rocas, Josep [et al.]. Installing multifunctionality on titanium with RGD-decorated polyurethane-polyurea roxithromycin loaded nanoparticles: toward new osseointegrative therapies. Advanced Healthcare Materials, 2015, 4(13), p. 1-5. Disponible en: <https://onlinelibrary.wiley.com/doi/full/10.1002/adhm.201500245>. Fecha de acceso: 17 jun. 2020. DOI: 10.1002/adhm.201500245
This item appears in the following Collection(s)
- Ciències de la Salut [740]
Rights
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Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by-nc-nd/4.0/