Browsing Ciències de la Salut by Title
Now showing items 1-20 of 915
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A 3-dimensional histology computer model of malignant melanoma and its implications for digital pathology
(European Journal of Cancer, 2023)Background: Historically, cancer diagnoses have been made by pathologists using two-dimensional histological slides. However, with the advent of digital pathology and artificial intelligence, slides are ... -
90 years of progesterone: molecular mechanisms of progesterone receptor action on the breast cancer genome
(Journal of Molecular Endocrinology, 2020)Gene regulation by steroid hormones has been at the forefront in elucidating the intricacies of transcriptional regulation in eukaryotes ever since the discovery by Karlson and Clever that the insect ... -
A barbed suture repair for flexor tendons: a novel technique with no exposed barbs
(Plastic and Reconstructive Surgery Global Open, 2014-10-23)Background: Barbed suture technology has shown promise in flexor tendon repairs, as there is an even distribution of load and the need for a knot is eliminated. We propose that a quick and simple, ... -
A dual molecular biointerface combining RGD and KRSR sequences Improves osteoblastic functions by synergizing integrin and cell-membrane proteoglycan binding
(International Journal of Molecular Sciences, 2019-03-21)Synergizing integrin and cell-membrane heparan sulfate proteoglycan signaling on biomaterials through peptidic sequences is known to have beneficial effects in the attachment and behavior of osteoblasts; ... -
A European evaluation of the patients’ role in clinical education: A six-country cross sectional study
(Nurse Education in Practice, 2022)Aim: The aim of this study was to analyse the patients’ role in clinical education in terms of facilitative student-patient relationship in Finland, Germany, Iceland, Ireland, Lithuania and Spain and ... -
A linear lesion in a child with atopic dermatitis: not a coincidence
(Clinical Case Reports, 2019-07-25)A blaschkolinear lesion in a patient with atopic dermatitis can be a superimposed segmental manifestation of this polygenic disorder. Knowledge of this phenomenon, presence of less severe, disseminated, ... -
A mini review focused on the proangiogenic role of silicate ions released from silicon-containing biomaterials
(2017-04-06)Angiogenesis is considered an important issue in the development of biomaterials for the successful regeneration of tissues including bone. While growth factors are commonly used with biomaterials to ... -
A mutation in the iron-responsive element of ALAS2 is a modifier of disease severity in a patient suffering from CLPX associated erythropoietic protoporphyria
(Haematologica, 2021)Porphyrias are a group of eight genetically distinct disorders, each resulting from a partial deficiency or gain-offunction of a specific enzyme in the heme biosynthetic pathway.1 Porphyrias are inherited ... -
A novel pathogenic variant in the KRT3 gene in a family with meesmann corneal dystrophy
(Journal of Clinical Medicine, 2025)Background/Objectives: to report a novel KRT3 Meesmann corneal dystrophy (MECD) mutation and its clinical findings in a Spanish family, thus completing the international database. Case series study. ... -
A nucleotide-based drug protects against glutamate- and MPP+ -induced neurotoxicity
(Neuroscience & Medicine, 2011)Nucleo CMP Forte® is a nucleotide-based drug consisting of cytidinemonophosphate, uridinemonophosphate, uridin-ediphosphate and uridinetriphosphate. It has been prescribed for peripheral nervous system ... -
A path analysis model of self- vs. educational-context- regulation as combined predictors of well-being in spanish college students
(International Journal of Environmental Reseacrh and Public Health, 2022)Previous literature has established the importance of personal and contextual factors in college students’ trajectories. Following the Self- vs. External-Regulation Behavior Theory (2021) and the 3P ... -
A personalizable autonomous neural mass model of epileptic seizures
(Journal of Neural Engineering, 2022)Work in the last two decades has shown that neural mass models (NMM) can realistically reproduce and explain epileptic seizure transitions as recorded by electrophysiological methods (EEG, SEEG). In ... -
A perspective on the role of physiological stresses in cancer, diabetes and cognitive disease as environmental diseases
(Frontiers in Molecular Biosciences, 2023)With rapid industrialization, urbanization, and climate change, the impact of environmental factors on human health is becoming increasingly evident and understanding the complex mechanisms involved is ... -
A program of telementoring in laparoscopic bariatric surgery
(Minimally Invasive Therapy & Allied Technologies, 2016)Background This study proposes a system for teaching and surgical support with the benefits of online Information and Communications Technology (ITC) -based telementoring for laparoscopic bariatric ... -
A quick diagnosis unit as an alternative to conventional hospitalization in a tertiary public hospital: a descriptive study
(Polish Archives of Internal Medicine, 2013-09-24)Introduction: Reports indicate that a significant number of patients admitted to internal medicine units could be studied on an outpatient basis. Objectives: This article assesses a quick diagnosis unit ... -
A retained intron in the 3′‐UTR of Calm3 mRNA mediates its Staufen2‐ and activity‐dependent localization to neuronal dendrites
(EMBO Reports, 2017)Dendritic localization and hence local mRNA translation contributes to synaptic plasticity in neurons. Staufen2 (Stau2) is a well‐known neuronal double‐stranded RNA‐binding protein (dsRBP) that has been ... -
A self-calibrating and multiplexed electrochemical lab-on-a-chip for cell culture analysis and high-resolution imaging
(Lab on a Chip, 2020)In vitro analysis requires cell proliferation in conditions close to physiological ones. Lab-on-a-chip (LoC) devices simplify, miniaturize and automate traditional protocols, with the advantages of being ... -
A short RNA stem–loop is necessary and sufficient for repression of gene expression during early logarithmic phase in trypanosomes
(Nucleic Acids Research, 2014)We have compared the transcriptomes of cultured procyclic Trypanosoma brucei cells in early and late logarithmic phases and found that ∼200 mRNAs were differentially regulated. In late log phase cells, ... -
A successful nursing education promotes newly graduated nurses’ job satisfaction one year after graduation: a cross-sectional multi-country study
(BMC Nursing, 2023)Background: Job satisfaction is a key factor for the successful transition of newly graduated nurses (NGNs) and for retaining NGNs in their workplaces. However, there is limited evidence of the relationship ... -
A systematic review of the relationship factor between women and health professionals within the multivariant analysis of maternal satisfaction
(Midwifery, 2016)Introduction: personalised support provided to women by health professionals is one of the prime factors attaining women's satisfaction during pregnancy and childbirth. However the multifactorial nature ...