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Fructose-1,6-bisphosphate prevents pulmonary fibrosis by regulating extracellular matrix deposition and inducing phenotype reversal of lung myofibroblasts
(Public Library of Science, 2019)
Pulmonary fibrosis (PF) is the result of chronic injury where fibroblasts become activated and secrete large amounts of extracellular matrix (ECM), leading to impaired fibroblasts degradation followed ...
Respiratory physiotherapy interventions used during hospitalization of children and adolescents with asthma
(Pontificia Universidad Católica de Río Grande del Sur, 2021)
Aims: to describe and to compare the airway clearance techniques used for asthma during hospitalization in three pediatric age groups. In addition, we sought to investigate the main reasons for choosing ...
Modified shuttle test distance correlates with peak oxygen uptake in children and adolescents with severe therapy-resistant asthma
(Frontiers Media, 2019)
Introduction: Several tests may be used to assess exercise intolerance in severe therapy-resistant asthma (STRA), including the gold standard cardiopulmonary exercise test (CPET) and the modified shuttle ...
Descriptive analysis of cystic fibrosis patients followed by the Pediatric Pulmonology Unit of a university hospital in Porto Alegre-RS
(Electronic Journal Publishing System, 2006)
Aims: To provide a descriptive analysis of patients followed in a local cystic fibrosis treatment center and compare the collected data with those found in the literature. Methods: Relevant data for ...
Effects and safety of hypertonic saline combined with airway clearance in non-hospitalized children with recurrent wheezing
(World Scientific Publishing, 2023)
Background: The International Study of Wheezing in Infants defines recurrent wheezing as the presence of three or more medically documented episodes of wheezing within one year. To date, there is no ...
Changes in lung function in adolescents with substance use disorders: an exploratory study
(Sociedade Brasileira de Pneumologia e Tisiologia, 2023)
Objective: To compare lung function between adolescents with and without substance use disorder (SUD). Methods: This was an observational, cross-sectional exploratory study. The sample consisted of 16 ...
Association of sleep disorders with heart rate variability in children and adolescents with cystic fibrosis
(Zeppelini Publishers, 2022)
Objective: To assess the association of sleep disorders with the findings of heart rate variability (HRV) in children and adolescents with cystic fibrosis (CF). Methods: Cross-sectional study including ...
Prenatal stress induces long-lasting effects in lung glucocorticoid receptor gene expression in a sex-dependent manner
(Scientia Medica, 2019)
AIM: Stressful events during pregnancy may influence respiratory system development, resulting in long-term effects in the offspring. However, little is known on its long-lasting effects upon the ...
Mechanisms of ventilatory limitation to maximum exercise in children and adolescents with chronic airway diseases
(John Wiley & Sons, 2023)
Introduction: Exercise intolerance is common in chronic airway diseases (CAD), but its mechanisms are still poorly understood. The aim of this study was to evaluate exercise capacity and its association ...
Cystic fibrosis in Brazil: achievements in survival
(Jornal Brasileiro de Pneumologia, 2021)