Modified shuttle test distance correlates with peak oxygen uptake in children and adolescents with severe therapy-resistant asthma
Author
Schiwe, Daniele
Heinzmann-Filho, João Paulo
Silva Schindel, Cláudia
Fátima Gheller, Mailise
Evangelista Campos, Natália
Márcio Pitrez, Paulo
Fagundes Donadio, Márcio Vinícius
Publication date
2019ISSN
1664-042X
Abstract
Introduction: Several tests may be used to assess exercise intolerance in severe therapy-resistant asthma (STRA), including the gold standard cardiopulmonary exercise test (CPET) and the modified shuttle test (MST). Objective: To correlate the distance achieved in the MST with peak oxygen uptake (VO2peak) and to compare the maximal heart rate (HRmax) obtained in both tests in children and adolescents with STRA. Methods: This is a cross-sectional study, with 19 children and adolescents with STRA. Demographic, anthropometric, clinical data, and spirometric values were collected. CPET and the MST were performed in two consecutive visits. HRmax, pulse oxygen saturation, and dyspnea were compared between tests. The distance achieved in the MST was correlated with VO2peak. Results: Nineteen patients with a mean age of 11.5 ± 2.5 years were included. The mean HRmax (bpm) achieved was 180.8 ± 12.10 for the MST and 187.6 ± 9.35 for CPET, whereas the mean HRmax as a percentage of predicted (HRmax%) was 90.7 ± 6.5 for the MST and 93.8 ± 4.5 for CPET. A difference of only 6 bpm was found for HRmax (p = 0.10) and of 3% for HRmax% (p = 0.06) between tests. A strong correlation was found between the MST (r = 0.79; p = 0.001) and VO2peak measured through CPET. However, there were no correlations between the MST and both body mass index (r = −0.14; p = 0.564) and forced expiratory volume in the first second – FEV1 (r = −0.02; p = 0.917). Conclusion: The results demonstrate that the MST distance strongly correlates with VO2peak, measured through CPET, and the main physiological variable responses were similar between both tests. Our results provide additional data for the use of the MST to assess exercise capacity in children and adolescents with STRA.
Document Type
Article
Document version
Published version
Language
English
Subject (CDU)
61 - Medical sciences
616.2 - Pathology of the respiratory system. Complaints of the respiratory organs
Keywords
Asma resistent a la teràpia severa
Esforç cardiopulmonar estàndard
Prova llançadora modificada
Asma resistente a la terapia severa
Esfuerzo cardiopulmonar estándar
Prueba lanzadera modificada
Asthma resistant to severe therapy
Standard cardiopulmonary exertion
Modified shuttle test
Pages
8
Publisher
Frontiers Media
Collection
10;
Is part of
Frontiers in Physiology
Citation
Schiwe, Daniele; Heinzmann-Filho, João Paulo; Silva Schindel, Cláudia [et al.]. Modified shuttle test distance correlates with peak oxygen uptake in children and adolescents with severe therapy-resistant asthma. Frontiers in Physiology, 2019, 10, 1245. Disponible en: <https://www.frontiersin.org/articles/10.3389/fphys.2019.01245/full>. Fecha de acceso: 22 mar. 2022. DOI: 10.3389/fphys.2019.01245.
This item appears in the following Collection(s)
- Ciències de la Salut [745]
Rights
© 2019 Schiwe, Heinzmann-Filho, Schindel, Gheller, Campos, Pitrez and Donadio. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by/4.0/