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ADP-ribose–derived nuclear ATP synthesis by NUDIX5 is required for chromatin remodeling
(American Association for the Advancement of Science, 2016)
Key nuclear processes in eukaryotes, including DNA replication, repair, and gene regulation, require extensive chromatin remodeling catalyzed by energy-consuming enzymes. It remains unclear how the ATP ...
Effectiveness of a multicomponent training program on physical performance and muscle quality in older adults: a quasi-experimental study
(MDPI, 2023)
Aging is associated with a decrease in functional capacity, manifested by a loss of strength, physical performance and muscle quality. Multicomponent training (MCT), characterized by the combination of ...
Chronic full-band recordings with graphene microtransistors as neural interfaces for discrimination of brain states
(Royal Society of Chemistry, 2024)
Brain states such as sleep, anesthesia, wakefulness, or coma are characterized by specific patterns of cortical activity dynamics, from local circuits to full-brain emergent properties. We previously ...
Skull fractures by glass bottles tested on cadaveric heads
(Springer Nature, 2023)
Head trauma is frequently related to the misuse of drinking vessels as weapons. Forensic reports usually evaluate these blunt injuries as having occurred in scenarios where the alcohol intake is high. ...
Investigating the thermodynamics of small biosystems with optical tweezers
(Elsevier, 2010)
We present two examples of how single-molecule experimental techniques applied to biological systems can give insight into problems within the scope of equilibrium and nonequilibrium mesoscopic ...
Assessing the potential role of copper and cobalt in stimulating angiogenesis for tissue regeneration
(Public Library of Science, 2021)
The use of copper (Cu2+) and cobalt (Co2+) has been described to stimulate blood vessel formation, a key process for the success of tissue regeneration. However, understanding how different concentrations ...
Structural characterization of NORAD reveals a stabilizing role of spacers and two new repeat units
(Elsevier, 2021)
Long non-coding RNAs (lncRNAs) can perform a variety of key cellular functions by interacting with proteins and other RNAs. Recent studies have shown that the functions of lncRNAS are largely mediated ...
Rationally designed azobenzene photoswitches for efficient two-photon neuronal excitation
(Springer Nature, 2019)
Manipulation of neuronal activity using two-photon excitation of azobenzene photoswitches with near-infrared light has been recently demonstrated, but their practical use in neuronal tissue to photostimulate ...
Improved dynamical particle swarm optimization method for structural dynamics
(Hindawi, 2019)
A methodology to the multiobjective structural design of buildings based on an improved particle swarm optimization algorithm is presented, which has proved to be very efficient and robust in nonlinear ...
Single-molecule stochastic resonance
(American Physical Society, 2012)
Stochastic resonance (SR) is a well-known phenomenon in dynamical systems. It consists of the amplification and optimization of the response of a system assisted by stochastic (random or probabilistic) ...