Ciències de la Salut: Recent submissions
Now showing items 921-940 of 1006
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Biofunctionalization with a TGFβ-1 inhibitor peptide in the osseointegration of synthetic bone grafts: an in vivo study in beagle dogs
(Materials, 2019-09-27)Objectives: The aim of this research was to determine the osseointegration of two presentations of biphasic calcium phosphate (BCP) biomaterial—one untreated and another submitted to biofunctionalization ... -
Comprehensive and quantitative analysis of G1 cyclins. A tool for studying the cell cycle
(PLoS One, 2019-06-25)In eukaryotes, the cell cycle is driven by the actions of several cyclin dependent kinases (CDKs) and an array of regulatory proteins called cyclins, due to the cyclical expression patterns of the latter. ... -
Educational climate perception by preclinical and clinical medical students in five Spanish medical schools
(International Journal of Medical Education, 2015-06-08)Objectives: The purpose of this study was to investigate student’s perceptions of Educational Climate (EC) in Spanish medical schools, comparing various aspects of EC between the 2nd (preclinical) and ... -
Evidence of functional declining and global comorbidity measured at baseline proved to be the strongest predictors for long-term death in elderly community residents aged 85 years: a 5-year follow-up evaluation, the OCTABAIX study
(Clinical Interventions in Aging, 2016-04-18)Objective: To investigate the predictive value of functional impairment, chronic conditions, and laboratory biomarkers of aging for predicting 5-year mortality in the elderly aged 85 years. Methods: ... -
Hypothalamic endocannabinoids inversely correlate with the development of diet-induced obesity in male and female mice
(Journal of Lipid Research, 2019-07)The endocannabinoid (eCB) system regulates energy homeostasis and is linked to obesity development. However, the exact dynamic and regulation of eCBs in the hypothalamus during obesity progression remain ... -
Perception of quality of care of patients with potentially severe diseases evaluated at a distinct quick diagnostic delivery model: a cross-sectional study
(BMC Health Services Research, 2015-09-30)Background: Although hospital-based outpatient quick diagnosis units (QDU) are an increasingly recognized cost-effective alternative to hospitalization for the diagnosis of potentially serious diseases, ... -
Aprendizaje de las competencias de investigación en el Grado de Medicina: análisis y evaluación de las calificaciones de los estudiantes en el Trabajo de Final de Grado
(Anales de Psicología, 2016)La adaptación al Plan Bolonia del Grado de Medicina en España ha introducido en los planes de estudio la realización del Trabajo de Final de Grado (TFG). A continuación se presenta un modelo de TFG y ... -
Psychometric properties of the spanish version of the Jefferson Scale of Empathy: making sense of the total score through a second order confirmatory factor analysis
(BMC Medical Education, 2016-09-19)Background: Empathy is a key aspect of the physician-patient interactions. The Jefferson Scale of Empathy (JSE) is one of the most used empathy measures of medical students. The development of cross-cultural ... -
Gender differences in labour losses associated with smoking-related mortality
(International Journal of Environmental Research and Public Health, 2019-09-28)The aim of this paper was to estimate the number of premature deaths, years of potential productive life lost (YPPLL) and labour losses attributable to tobacco smoking due to premature death by gender ... -
Ultrasensitive photonic microsystem enabling sub-micrometric monitoring of arterial oscillations for advanced cardiovascular studies
(Frontiers in Physiology, 2019-07-23)Cardiovascular diseases are the first cause of death globally. Their early diagnosis requires ultrasensitive tools enabling the detection of minor structural and functional alterations in small arteries. ... -
Mevalonate pathway activity as a determinant of radiation sensitivity in head and neck cancer
(Molecular Oncology, 2019-06-21)Radioresistance is a major hurdle in the treatment of head and neck squamous cell carcinoma (HNSCC). Here, we report that concomitant treatment of HNSCCs with radiotherapy and mevalonate pathway inhibitors ... -
The quantitative changes in the yeast Hsp70 and Hsp90 interactomes upon DNA damage
(Data in Brief, 2015-03)The molecular chaperones Hsp70 and Hsp90 participate in many important cellular processes, including how cells respond to DNA damage. Here we show the results of applied quantitative affinity-purification ... -
Critical update for the clinical use of L-carnitine analogs in cardiometabolic disorders
(Vascular Health and Risk Management, 2011-03-28)Acetyl-L-carnitine (ALC) and propionyl-L-carnitine (PLC) are two naturally occurring carnitine derivates formed by carnitine acetyltransferase. The beneficial cardiovascular effects of ALC and PLC have ... -
Characterization of ferrofluid-based stimuli-responsive elastomers
(Frontiers in Mechanical Engineering, 2016-12-12)Stimuli-responsive materials undergo physicochemical and/or structural changes when a specific actuation is applied. They are heterogeneous composites, consisting of a non-responsive matrix where ... -
Effectiveness of a specific manual approach to the suboccipital region in patients with chronic mechanical neck pain and rotation deficit in the upper cervical spine: study protocol for a randomized controlled trial
(BMC Musculoskeletal Disorders, 2017-09-05)This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and ... -
High-flow nasal cannula to prevent postextubation respiratory failure in high-risk non-hypercapnic patients: a randomized multicenter trial
(Annals of Intensive Care, 2017-05-02)Background: Extubation failure is associated with increased morbidity and mortality, but cannot be safely predicted or avoided. High-flow nasal cannula (HFNC) prevents postextubation respiratory failure ... -
Automatic detection of ventilatory modes during invasive mechanical ventilation
(Critical Care, 2016-08-14)Background: Expert systems can help alleviate problems related to the shortage of human resources in critical care, offering expert advice in complex situations. Expert systems use contextual information ... -
Effectiveness of a Surgery Admission Unit for patients undergoing major elective surgery in a tertiary university hospital
(BMC Health Services Research, 2010-01-22)Background: The increasing demand on hospitalisation, either due to elective activity from the waiting lists or due to emergency admissions coming from the Emergency Department (ED), requires looking ... -
ALCAM shedding at the invasive front of the tumor is a marker of myometrial infiltration and promotes invasion in endometrioid endometrial cancer
(Oncotarget, 2018-03-30)Endometrial cancer (EC) is the sixth deadliest cancer in women. The depth of myometrial invasion is one of the most important prognostic factors, being directly associated with tumor recurrence and ... -
Standardizing admission and discharge processes to improve patient flow: a cross sectional study
(BMC Health Services Research, 2012-06-28)Background: The aim of this study was to evaluate how hospital capacity was managed focusing on standardizing the admission and discharge processes. Methods: This study was set in a 900-bed university ...