Ciències de la Salut: Recent submissions
Now showing items 821-840 of 979
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A truncated form of IKKa is responsible for specific nuclear IKK activity in colorectal cancer
(Cell Reports, 2012-10-25)Nuclear IKKα regulates gene transcription by phosphorylating specific substrates and has been linked to cancer progression and metastasis. However, the mechanistic connection between tumorigenesis and ... -
Simulation methods with extended stability for stiff biochemical Kinetics
(BMC Systems Biology, 2010)Background: With increasing computer power, simulating the dynamics of complex systems in chemistry and biology is becoming increasingly routine. The modelling of individual reactions in (bio)chemical ... -
Antiretroviral therapy suppressed participants withlow CD4RT-cell counts segregate according toopposite immunological phenotypes
(AIDS, 2016-09)Background:The failure to increase CD4þT-cell counts in some antiretroviral therapysuppressed participants (immunodiscordance) has been related to perturbed CD4þT-cell homeostasis and impacts clinical ... -
Surgical management for refractory bleb dysesthesia
(Journal of Ophthalmology, 2020-08)Purpose. To present long-term results of modified bleb-limiting conjunctivoplasty as a successful treatment for intractable bleb dysesthesia and to review the literature on the surgical management of ... -
Real-world epidemiology of potassium derangements among chronic cardiovascular, metabolic and renal conditions: a population-based analysis
(Clinical Epidemiology, 2020)Background: The aims of the present analysis are to estimate the prevalence of five key chronic cardiovascular, metabolic and renal conditions at the population level, the prevalence of renin–angioten ... -
Validity and reliability of the satel 40 Hz stabilometric force platform for measuring quiet stance and dynamic standing balance in healthy subjects
(International Journal of Environmental Research and Public Health, 2020)Background: A force platform must have validity and reliability for optimal use. The objective of this study was to analyze the validity and the reliability of the Satel 40 Hz stabilometric force platform. ... -
Development and validation of a sample entropy-based method to identify complex patient-ventilator interactions during mechanical ventilation
(Scientific Reports, 2020)Patient-ventilator asynchronies can be detected by close monitoring of ventilator screens by clinicians or through automated algorithms. However, detecting complex patient-ventilator interactions (CP-VI), ... -
Sensing of nutrients by CPT1C controls SAC1 activity to regulate AMPA receptor trafficking
(Journal of Cell Biology, 2020-09)Carnitine palmitoyltransferase 1C (CPT1C) is a sensor of malonyl-CoA and is located in the ER of neurons. AMPA receptors (AMPARs) mediate fast excitatory neurotransmission in the brain and play a key ... -
Lower admission blood pressure as an independent predictor of 1-year mortality in elderly patients experiencing a first hospitalization for acute heart failure
(Hellenic Journal of Cardiology, 2019)Background: Systolic blood pressure (SBP) is an acknowledged prognostic factor in patients with heart failure (HF). Admission SBP should be a risk factor for 1-year mortality even in elderly patients ... -
Effect of different implant designs on strain and stress distribution under non-axial loading: a three-dimensional finite element analysis
(International Journal of Environmental Research and Public Health, 2020)Implant design evolved alongside the development of implant therapy. The purpose of this finite element analysis (FEA) study was to analyze the influence of different implant designs on the stress and ... -
Platelet-rich plasma and its use for cicatricial and non-cicatricial alopecias: a narrative review
(Dermatology and Therapy, 2020-06)The concept and description of platelet-rich plasma (PRP) started in the field of hematology and is being extensively used in other fields of medicine. Interest in the application of PRP has been ... -
Reconfigurable multiplexed point of care system for monitoring type 1 diabetes patients
(Biosensors and Bioelectronics, 2019-07)At the point of care (POC), on-side clinical testing allows fast biomarkers determination even in resource-limited environments. Current POC systems rely on tests selective to a single analyte or complex ... -
CPT1c is localized in endoplasmic reticulum of neurons and has carnitine palmitoyltransferase activity
(Journal of Biological Chemistry, 2008)CPT1c is a carnitine palmitoyltransferase 1 (CPT1) isoform that is expressed only in the brain. The enzyme has recently been localized in neuron mitochondria. Although it has high sequence identity with ... -
Prevalence of prediabetes and associated factors in the oldest old: a cross sectional study in the octabaix cohort
(International Journal of Gerontology, 2017-06)Background: The leading high-risk state for diabetes mellitus (DM) – prediabetes – is increasing; however, a lack of information exists in oldest old subjects. The objective of this study is to describe ... -
Burden of disease attributable to second-hand smoke exposure: a systematic review
(Preventive Medicine, 2019-12)Our aim was to provide a systematic review of studies on the burden of disease due to second-hand smoke (SHS) exposure, reviewing methods, exposure assessment, diseases causally linked to SHS, health ... -
Sarcoma de Kaposi de diagnóstico intraoral
(Revista Española de Cirugía Oral y Maxilofacial, 2017) -
Evaluation of bone loss in antibacterial coated dental implants: an experimental study in dogs
(Materials Science and Engineering: C, 2016-12)The aim of this study was to evaluate the in vivo effect of antibacterial modified dental implants in the first stages of peri-implantitis. Thirty dental implants were inserted in the mandibular premolar ... -
Tricholeichomania by proxy
(Journal of Clinical Medical Research, 2020) -
Differential HMG‐CoA lyase expression in human tissues provides clues about 3‐hydroxy‐3‐methylglutaric aciduria
(Journal of Inherited Metabolic Disease, 2010)3‐Hydroxy‐3‐methylglutaric aciduria is a rare human autosomal recessive disorder caused by deficiency of 3‐hydroxy‐3‐methylglutaryl CoA lyase (HL). This mitochondrial enzyme catalyzes the common final ... -
Isolated acute hemorrhagic edema of the eyelids
(Journal of Respiratory Research, 2019-12)Perivascular epithelioid cell tumors (PEComas) are rare tumors which can arise in almost every body site. Little is still known about these tumors because of the limited number of cases described by far ...