Now showing items 801-820 of 979

    • Current challenges for targeting brown fat thermogenesis to combat obesity 

      Yoneshiro, Takeshi; Rodríguez-Rodríguez, Rosalía; Johannes Betz, Matthias; Rensen, Patrick C. N. (Frontiers in Endocrinology, 2020-10-27)
      Just over a decade has passed since metabolically active brown adipose tissue (BAT) was unequivocally identified in healthy adult humans. Since then, researchers have provided evidence of expression of ...
    • Comparación en la adquisición y retención de competencias en soporte vital entre formación uni o interdisciplinar. Estudio cuasiexperimental 

      Castillo Garcia, Jordi; Llauradó Serra, Mireia; Aliberch Raurell, Anna; Rodriguez Higueras, Encarnación (Atención Primaria, 2020-05)
      Se realizó un estudio prospectivo cuasiexperimental con el objetivo de evaluar las competencias de los estudiantes de enfermería después de un curso oficial en soporte vital básico (SVB) y uso del ...
    • Predicting clinical outcome with phenotypic clusters in COVID-19 pneumonia: an analysis of 12,066 hospitalized patients from the spanish registry SEMI-COVID-19 

      Rubio-Rivas, Manuel; Corbella Virós, Xavier; Mora-Luján, José María; Loureiro-Amigo, José; López Sampalo, Almudena; Yera Bergua, Carmen; Esteve Atiénzar, Pedro Jesús; Díez García, Luis Felipe; Gonzalez Ferrer, Ruth; Plaza Canteli, Susana; Pérez Piñeiro, Antía; Cortés Rodríguez, Begoña; Jorquer Vidal, Leyre; Pérez Catalán, Ignacio; León Téllez, Marta; Martín Oterino, José Ángel; Martín González, María Candelaria; Serrano Carrillo de Albornoz, José Luis; García Sardon, Eva; Alcalá Pedrajas, José Nicolás; Martin-Urda Diez-Canseco, Anabel; Esteban Giner, María José; Tellería Gómez, Pablo; Ramos-Rincón, José Manuel; Gómez-Huelgas, Ricardo (Journal of Clinical Medicine, 2020)
      (1) Background: Different clinical presentations in COVID-19 are described to date, from mild to severe cases. This study aims to identify different clinical phenotypes in COVID-19 pneumonia using cluster ...
    • Beneficial effect of corticosteroids in preventing mortality in patients receiving tocilizumab to treat severe COVID-19 illness 

      Rubio-Rivas, Manuel; Ronda, Mar; Padullés, Ariadna; Mitjavila, Francesca; Riera-Mestre, Antoni; García-Forero, Carlos; Iriarte, Adriana; Mora-Luján, José María; Padullés, Núria; Gonzalez, Monica; Solanich, Xavier; Gasa, Merce; Suarez-Cuartin, Guillermo; Sabater-Riera, Joan; Perez-Fernandez, Xose L.; Santacana, Eugenia; Leiva, Elisabet; Ariza-Sole, Albert; Dallaglio, Paolo D.; Quero, Maria; Soriano, Antonio; Pasqualetto, Alberto; Koo, Maylin; Esteve-Luque, Virginia; Antolí, Arnau; Moreno-Gónzalez, Rafael; Yun, Sergi; Cerdà, Pau; Llaberia, Mariona; Formiga, Francesc; Fanlo-Maresma, Marta; Montero, Abelardo; Chivite, David; Capdevila, Olga; Bolao, Ferran; Pintó, Xavier; Llop, Josep; Sabate, Antoni; Guardiola, Jordi; Cruzado, Josep M.; Comin-Colet, Josep; Santos, Salud; Jodar, Ramon; Corbella Virós, Xavier (Elsevier, 2020-12)
      Objectives: To assess the characteristics and risk factors for mortality in patients with severe coronavirus disease-2019 (COVID-19) treated with tocilizumab (TCZ), alone or in combination with ...
    • Chronic kidney disease in the context of multimorbidity patterns: the role of physical performance: the screening for CKD among older people across Europe (SCOPE) study 

      Corsonello, Andrea; Fabbietti, Paolo; Formiga, Francesc; Moreno-Gónzalez, Rafael; Tap, Lisanne; Mattace-Raso, Francesco; Roller-Wirnsberger, Regina; Wirnsberger, Gerhard; Ärnlöv, Johan; Carlsson, Axel C.; Weingart, Christian; Freiberger, Ellen; Kostka, Tomasz; Guligowska, Agnieszka; Gil, Pedro; Laínez Martínez, Sara; Melzer, Itshak; Yehoshua, Ilan; Lattanzio, Fabrizia; SCOPE investigators; Corbella Virós, Xavier (BMC Geriatrics, 2020-10-02)
      Background: Chronic kidney disease (CKD) is known to be associated with several co-occurring conditions. We aimed at exploring multimorbidity patterns associated with CKD, as well as the impact of ...
    • Association between kidney function, nutritional status and anthropometric measures in older people: the screening for CKD among older people across Europe (SCOPE) study 

      Guligowska, Agnieszka; Corsonello, Andrea; Pigłowska, Małgorzata; Roller-Wirnsberger, Regina; Wirnsberger, Gerhard; Ärnlöv, Johan; Carlsson, Axel C.; Tap, Lisanne; Mattace-Raso, Francesco; Formiga, Francesc; Moreno-Gónzalez, Rafael; Freiberger, Ellen; Sieber, Cornel; Gregorio, Pedro Gil; Laínez Martínez, Sara; Artzi-Medvedik, Rada; Yehoshua, Ilan; Fabbietti, Paolo; Lattanzio, Fabrizia; Kostka, Tomasz; SCOPE investigators; Corbella Virós, Xavier (BMC Geriatrics, 2020-10-02)
      Background: Different mechanisms connect the nutritional status with the occurrence and the course of chronic kidney disease (CKD). The end-stage renal disease is complicated by catabolic inflammatory ...
    • Prevalence of sarcopenia in community-dwelling older adults using the updated EWGSOP2 definition according to kidney function and albuminuria 

      Moreno-Gónzalez, Rafael; Corbella Virós, Xavier; Mattace-Raso, Francesco; Tap, Lisanne; Sieber, Cornel; Freiberger, Ellen; Kostka, Tomasz; Guligowska, Agnieszka; Melzer, Itshak; Melzer, Yehudit; Carlsson, Axel C.; Ärnlöv, Johan; Roller-Wirnsberger, Regina; Wirnsberger, Gerhard; Gil, Pedro; Laínez Martínez, Sara; Fabbietti, Paolo; Corsonello, Andrea; Lattanzio, Fabrizia; Formiga, Francesc; SCOPE investigators (BMC Geriatrics, 2020-10-02)
      Background: Loss of muscle mass and function may be more pronounced in older adults with chronic kidney disease (CKD) and with albuminuria. Thus, we investigated the prevalence of sarcopenia among ...
    • Real-world epidemiology of potassium derangements among chronic cardiovascular, metabolic and renal conditions: a population-based analysis 

      Jiménez-Marrero, Santiago; Cainzos-Achirica, Miguel; Monterde, David; Garcia-Eroles, Luis; Enjuanes-Grau, Cristina; Yun, Sergi; Garay, Alberto; Moliner, Pedro; Alcoberro, Lidia; Corbella Virós, Xavier; Comin-Colet, Josep (Clinical Epidemiology, 2020-09-11)
      Background: The aims of the present analysis are to estimate the prevalence of five key chronic cardiovascular, metabolic and renal conditions at the population level, the prevalence of renin–angioten ...
    • Does upper cervical manual therapy provide additional benefit in disability and mobility over a physiotherapy primary care program for chronic cervicalgia? A randomized controlled trial 

      González Rueda, Vanessa; Hidalgo-García, César; Rodríguez-Sanz, Jacobo; Bueno-Gracia, Elena; Pérez Bellmunt, Albert; Rodríguez-Rubio, Pere Ramón; López-de-Celis, Carlos (International Journal of Environmental Research and Public Health, 2020-11-11)
      Introduction: Neck pain is a condition with a high incidence in primary care. Patients with chronic neck pain often experience reduction in neck mobility. However, no study to date has investigated the ...
    • Gender differences in health-related quality of life in patients with systolic heart failure: results of the VIDA multicenter study 

      Garay, Alberto; Tapia, Javier; Anguita, Manuel; Formiga, Francesc; Almenar, Luis; Crespo-Leiro, María G.; Manzano, Luis; Muñiz, Javier; Chaves, José; De Frutos, Trinidad; Moliner, Pedro; Corbella Virós, Xavier; Enjuanes-Grau, Cristina; Comin-Colet, Josep; VIDA-IC Multicenter Study Investigators (Journal of Clinical Medicine, 2020-08-31)
      Previous studies have shown that heart failure is associated with worse health-related quality of life (HRQoL). The existence of differences according to gender remains controversial. We studied 1028 ...
    • An effect of bilingualism on the auditory cortex 

      Ressel, Volker; Pallier, Christopher; Ventura-Campos, Noelia; Díaz Menéndez, Begoña; Roessler, Abeba; Ávila, César; Sebastián-Gallés, Núria (Journal of Neuroscience, 2012-11)
      Two studies (Golestani et al., 2007; Wong et al., 2008) have reported a positive correlation between the ability to perceive foreign speech sounds and the volume of Heschl's gyrus (HG), the structure ...
    • Study design of heart failure events reduction with remote monitoring and eHealth support (HERMeS) 

      Yun, Sergi; Enjuanes-Grau, Cristina; Calero, Esther; Hidalgo, Encarnación; Cobo, Marta; Llàcer, Pau; García Pinilla, José Manuel; González Franco, Álvaro; Núñez, Julio; Morales Rull, José Luis; Beltrán, Paola; Delso, Cristina; Freixa Pamias, Román; Moliner, Pedro; Corbella Virós, Xavier; Comin-Colet, Josep; HERMeS trial investigators group (ESC Heart Failure, 2020)
      Aims: The role of non‐invasive telemedicine (TM) combining telemonitoring and teleintervention by videoconference (VC) in patients recently admitted due to heart failure (HF) (‘vulnerable phase’ HF ...
    • Sensing of nutrients by CPT1C controls SAC1 activity to regulate AMPA receptor trafficking 

      Casas, Maria; Fadó Andrés, Rut; Domínguez, José Luis; Roig, Aina; Kaku, Moena; Chohnan, Shigeru; Solé, Montse; Unzeta, Mercedes; Miñano Molina, Alfredo Jesús; Rodríguez-Álvarez, José; Dickson, Eamonn James; Casals i Farré, Núria (Journal of Cell Biology, 2020)
      Carnitine palmitoyltransferase 1C (CPT1C) is a sensor of malonyl-CoA and is located in the ER of neurons. AMPA receptors (AMPARs) mediate fast excitatory neurotransmission in the brain and play a key ...
    • Complete loss of EPCAM immunoexpression identifies EPCAM deletion carriers in MSH2-negative colorectal neoplasia 

      Cuatrecasas, Míriam; Gorostiaga, Iñigo; Riera, Cristina; Saperas, Esteban; Llort, Gemma; Costa, Irmgard; Matias-Guiu, Xavier; Carrato, Cristina; Navarro, Matilde; Pineda, Marta; Dueñas, Núria; Brunet, Joan; Marco, Vicente; Trias, Isabel; Busteros, José Ignacio; Mateu, Gemma; Balaguer, Francesc; Fernández-Figueras, María-Teresa; Esteller, Manel; Musulén, Eva (MDPI, 2020)
      The use of epithelial cell adhesion molecule (EPCAM) immunohistochemistry (IHC) is not included in the colorectal cancer (CRC) screening algorithm to detect Lynch syndrome (LS) patients. The aim of the ...
    • Word frequency cues word order in adults: cross-linguistic evidence 

      Gervain, Judit; Sebastián-Gallés, Núria; Diaz, Begoña; Laka, Itziar; Mazuka, Reiko; Yamane, Naoto; Nespor, Marina; Mehler, Jacques (Frontiers in Psychology, 2013-10-02)
      One universal feature of human languages is the division between grammatical functors and content words. From a learnability point of view, functors might provide entry points or anchors into the syntactic ...
    • Oscillation encoding of individual differences in speech perception 

      Jin, Yu; Díaz Menéndez, Begoña; Colomer, Marc; Sebastián-Gallés, Núria (PLoS One, 2014-07-03)
      Individual differences in second language (L2) phoneme perception (within the normal population) have been related to speech perception abilities, also observed in the native language, in studies assessing ...
    • Electrophysiological correlates of second-language syntactic processes are related to native and second language distance regardless of age of acquisition 

      Díaz Menéndez, Begoña; Erdocia, Kepa; De Menezes, Robert F.; Mueller, Jutta L.; Sebastián-Gallés, Núria; Laka, Itziar (Frontiers in Psychology, 2016-02-12)
      In the present study, we investigate how early and late L2 learners process L2 grammatical traits that are either present or absent in their native language (L1). Thirteen early (AoA = 4 years old) and ...
    • Liver CPT1A gene therapy reduces diet‐induced hepatic steatosis in mice and highlights potential lipid biomarkers for human NAFLD 

      Weber, Minéia; Mera, Paula; Casas, Josefina; Salvador, Javier; Rodríguez, Amaia; Alonso, Sergio; Sebastián, David; Soler-Vázquez, M. Carmen; Montironi, Carla; Recalde, Sandra; Fucho, Raquel; Calderón-Domínguez, María; Mir, Joan Francesc; Bartrons, Ramon; Escola-Gil, Joan Carles; Sánchez-Infantes, David; Zorzano, Antonio; Llorente-Cortes, Vicenta; Casals i Farré, Núria; Valentí, Víctor; Frühbeck, Gema; Herrero Rodríguez, Laura; Serra, Dolors (Federation of American Societies for Experimental Biology, 2020)
      The prevalence of nonalcoholic fatty liver disease (NAFLD) has increased drastically due to the global obesity pandemic but at present there are no approved therapies. Here, we aimed to revert high‐fat ...
    • Humo de tercera mano y otros retos del control del tabaquismo en población pediátrica 

      Lidón Moyano, Cristina; Díez-Izquierdo, Ana; Martínez Sánchez, Jose María (Anales de Pediatría, 2020)
    • Knowledge management for systems biology a general and visually driven framework applied to translational medicine 

      Maier, Dieter; Kalus, Wenzel; Wolff, Martin; Kalko, Susana G.; Roca, Josep; Marin de Mas, Igor; Turan, Nil; Cascante, Marta; Falciani, Francesco; Hernandez, Miguel; Villà-Freixa, Jordi; Losko, Sascha (BMC Systems Biology, 2011)
      Background: To enhance our understanding of complex biological systems like diseases we need to put all of the available data into context and use this to detect relations, pattern and rules which allow ...