Ara mostrant els elements 621-640 de 1006

    • Incidence and risk factors for trocar-site incisional hernia detected by clinical and ultrasound examination: a prospective observational study 

      Ciscar Bellés, Ana; Badia, Josep M; Novell, Francesc; Bolívar, Santiago; Mans, Esther (BMC Surgery, 2020)
      Background: Trocar site incisional hernia (TSIH) is the most frequent complication associated with laparoscopic surgery. Few studies currently describe its incidence or risk factors. The aim of this ...
    • The persistent breach between evidence and practice in the prevention of surgical site infection. Qualitative study 

      Badia, Josep M.; Rubio-Pérez, Inés; López-Menéndez, José; Diez, Cecilia; Al-Raies Bolaños, Bader; Ocaña-Guaita, Julia; Meijome, Xose M.; Chamorro-Pons, Manuel; Calderón-Nájera, Ramón; Ortega-Pérez, Gloria; Paredes-Esteban, Rosa; Sánchez-Viguera, Cristina; Vilallonga, Ramon; Picardo, Antonio L.; Bravo-Brañas, Elena; Espin, Eloy; Balibrea, José M.; Spanish Observatory of Surgical Infection (International Journal of Surgery, 2020)
      Background: Despite the dissemination of guidelines for surgical site infection (SSI) prevention, a gap between the theoretical measures and their compliance persists. Accurate estimates of the ...
    • Implementación de las recomendaciones para la prevención de infección de localización quirúrgica en España: encuesta para evaluación de discrepancias con la práctica clínica en cirugía cardiovascular 

      López-Menéndez, José; Varela, Laura; Rodríguez-Roda, Jorge; Castaño, Mario; Badia, Josep M.; Balibrea, José M.; Centella, Tomasa (Cirugía Cardiovascular, 2020)
      Introducción: Un panel nacional de expertos de sociedades científicas quirúrgicas ha resaltado su preocupación por el desconocimiento del grado de implementación de las medidas basadas en la evidencia ...
    • Hypothalamic regulation of obesity 

      Rodríguez-Rodríguez, Rosalía; Miralpeix , Cristina (International Journal of Molecular Sciences, 2021)
      Obesity has now reached pandemic proportions and represents a major socioeconomic and health problem in our societies. Up to now, obesity has been considered a medical issue only in high-income countries, ...
    • How did the COVID-19 lockdown affect children and adolescent's well-being: spanish parents, children, and adolescents respond 

      Ajanovic, Sara; Garrido-Aguirre, Jon; Baro, Bàrbara; Balanza, Núria; Varo, Rosauro; Millat-Martínez, Pere; Arias, Sara; Fonollosa, Jordi; Perera-Lluna, Alexandre; Jordan, Iolanda; Muñoz-Almagro, Carmen; Bonet-Carne, Elisenda; Crosas-Soler, Aina; Via, Esther; Nafria, Begonya; García-García, Juan José; Bassat, Quique (Frontiers in Public Health, 2021)
      Background: During the COVID-19 pandemic, lockdown strategies have been widely used to contain SARS-CoV-2 virus spread. Children and adolescents are especially vulnerable to suffering psychological ...
    • Socio-economic and psychological impact of COVID-19 pandemic in a Spanish cohort BIOVAL-D-COVID-19 study protocol 

      Miranda-Mendizábal, Andrea; Recoder, Silvia; Calbo, Esther; Casajuana Closas, Marc; Leiva Urena, David; Manolov, Rumen; Matilla Santander, Nuria; García Forero, Carlos; Castellví Obiols, Pere (Gaceta Sanitaria, 2021)
      Objective: SARS-CoV-2 outbreak has a negative psychological impact among general population. Data comparing mental health status before and during the outbreak is needed. The BIOVAL-D-COVID-19 study ...
    • Hypothalamic endocannabinoids in obesity: an old story with new challenges 

      Miralpeix , Cristina; Reguera, Ana Cristina; Fosch, Anna; Zagmutt, Sebastián; Casals i Farré, Núria; Cota, Daniela; Rodríguez-Rodríguez, Rosalía (Cellular and Molecular Life Sciences, 2021)
      The crucial role of the hypothalamus in the pathogenesis of obesity is widely recognized, while the precise molecular and cellular mechanisms involved are the focus of intense research. A disrupted ...
    • Differential nasopharyngeal microbiota composition in children according to respiratory health status 

      Henares, Desirée; Brotons de los Reyes, Pedro; de Sevilla, Mariona F; Fernandez-Lopez, Ana; Hernández-Bou, Susanna; Perez-Arguello, Amaresh; Mira, Alex; Muñoz-Almagro, Carmen; Cabrera-Rubio, Raúl (Microbial Genomics, 2021)
      Acute respiratory infections (ARIs) constitute one of the leading causes of antibiotic administration, hospitalization and death among children <5 years old. The upper respiratory tract microbiota has ...
    • Factors associated with depression and anxiety in adults ≥60 years old during the COVID-19 pandemic: a systematic review 

      Ciuffreda, Gianluca; Cabanillas Barea, Sara; Carrasco-Uribarren, Andoni; Albarova-Corral, María Isabel; Argüello-Espinosa, María Irache; Marcén-Román, Yolanda (International Journal of Environmental Research and Public Health, 2021)
      COVID-19 represents a threat to public health and the mental health of the aged population. Prevalence and risk factors of depression and anxiety have been reported in previous reviews in other populations; ...
    • Anthropometric measurements, metabolic profile and physical fitness in a sample of spanish women with type 2 diabetes 

      Lucha López, María Orosia; Vidal-Peracho, Concepcion; Hidalgo-García, César; Rodríguez-Sanz, Jacobo; Tricás-Vidal, Héctor; Hernández-Secorún, Mar; Monti-Ballano, Sofía; Tricás-Moreno, José Miguel; Lucha López, Ana Carmen (International Journal of Environmental Research and Public Health, 2021)
      Background: Exercise training has proven to be effective for treatment of metabolic diseases, such as type 2 diabetes mellitus. The aims of this study were to compare anthropometric measurements, metabolic ...
    • Respiratory physiotherapy interventions used during hospitalization of children and adolescents with asthma 

      Oppermann Ruckert, Daniele; Donadio, Marcio; Heinzmann-Filho, João Paulo (Scientia Medica, 2021)
      Aims: to describe and to compare the airway clearance techniques used for asthma during hospitalization in three pediatric age groups. In addition, we sought to investigate the main reasons for choosing ...
    • Expression of oncogenic drivers in 3D cell culture depends on nuclear ATP synthesis by NUDT5 

      Pickup, Katherine E.; Pardow, Felicitas; Carbonell-Caballero, José; Lioutas, Antonios; Villanueva-Cañas, José Luis; Wright, Roni; Beato, Miguel (Cancers, 2019)
      The growth of cancer cells as oncospheres in three-dimensional (3D) culture provides a robust cell model for understanding cancer progression, as well as for early drug discovery and validation. We have ...
    • Role of the NUDT enzymes in breast cancer 

      Wright, Roni; Beato, Miguel (International Journal of Molecular Sciences, 2021)
      Despite global research efforts, breast cancer remains the leading cause of cancer death in women worldwide. The majority of these deaths are due to metastasis occurring years after the initial treatment ...
    • Antibody conversion rates to SARS-CoV-2 in saliva from children attending summer schools in Barcelona, Spain 

      Dobaño, Carlota; Alonso, Selena; Fernández de Sevilla, Mariona; Vidal, Marta; Jiménez, Alfons; Pons Tomas, Gemma; Jairoce, Chenjerai; Melé Casas, María; Rubio, Rocío; Hernández García, María; Ruiz-Olalla, Gemma; Girona-Alarcón, Mònica; Barrios, Diana; Santano, Rebeca; Mitchell, Robert A.; Puyol, Laura; Mayer, Leonie; Chi, Jordi; Rodrigo Melero, Natalia; Carolis, Carlo; Garcia-Miquel, Aleix; Bonet-Carne, Elisenda; Claverol, Joana; Cubells, Marta; Fortuny, Claudia; Fumado, Vicky; Jou, Cristina; Muñoz-Almagro, Carmen; Izquierdo, Luis; Bassat, Quique; Gratacós, Eduard; Aguilar, Ruth; García-García, Juan José; Moncunill, Gemma; Jordan, Iolanda (BMC Medicine, 2021)
      Background: Surveillance tools to estimate viral transmission dynamics in young populations are essential to guide recommendations for school opening and management during viral epidemics. Ideally, ...
    • Apoyo a la regulación de fumar en el interior de vehículos privados y espacios públicos al aire libre 

      Cartanyà Hueso, Àurea; Lidón-Moyano, Cristina; Fu, Marcela; Ballbè, Montse; Martín-Sánchez, Juan Carlos; González-Marrón, Adrián; Matilla Santander, Nuria; Martínez-Sánchez, Jose M (Revista Española de Salud Pública, 2019)
      Fundamentos: Conocer el apoyo a la regulación del consumo de tabaco es una pieza clave para avanzar en las políticas de control del tabaquismo y reducir la exposición pasiva al tabaco. El objetivo de ...
    • Prevalencia de hogares libres de humo y exposición pasiva al tabaco en población pediátrica (niños de 3 a 36 meses) 

      Díez-Izquierdo, Ana; Cassanello Peñarroya, Pía; Cartanyà-Hueso, Àurea; Matilla-Santander, Nuria; Martínez-Sánchez, José María; Balaguer Santamaría, Albert; Martínez-Sánchez, José María (Revista Española de Salud Pública, 2019)
      Fundamentos: La población pediátrica es la más vulnerable a la exposición pasiva al humo ambiental del tabaco (HAT), siendo los hogares la fuente principal de exposición en niños. El objetivo de este ...
    • Hormone-control regions mediate steroid receptor–dependent genome organization 

      Le Dily, François; Vidal, Enrique; Cuartero, Yasmina; Quilez Oliete, Javier; Nacht, A. Silvina; Vicent, Guillermo P.; Carbonell-Caballero, José; Sharma, Priyanka; Villanueva-Cañas, José Luis; Ferrari, Roberto; De Llobet, Lara Isabel; Verde, Gaetano; Wright, Roni; Beato, Miguel (Genome Research, 2019)
      In breast cancer cells, some topologically associating domains (TADs) behave as hormonal gene regulation units, within which gene transcription is coordinately regulated in response to steroid hormones. ...
    • Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells 

      Page, Brent D.G.; Valerie, Nicholas C.K.; Wright, Roni H.G.; Wallner, Olov; Isaksson, Rebecka; Carter, Megan; Rudd, Sean G.; Loseva, Olga; Jemth, Ann-Sofie; Almlöf, Ingrid; Font-Mateu, Jofre; Llona-Minguez, Sabin; Baranczewski, Pawel; Jeppsson, Fredrik; Homan, Evert; Almqvist, Helena; Axelsson, Hanna; Regmi, Shruti; Gustavsson, Anna-Lena; Lundbäck, Thomas; Scobie, Martin; Strömberg, Kia; Stenmark, Pål; Beato, Miguel; Helleday, Thomas (Nature Communications, 2018)
      With a diverse network of substrates, NUDIX hydrolases have emerged as a key family of nucleotide-metabolizing enzymes. NUDT5 (also called NUDIX5) has been implicated in ADP-ribose and 8-oxo-guanine ...
    • Distinct structural transitions of chromatin topological domains correlate with coordinated hormone-induced gene regulation 

      Le Dily, François; Bau, Davide; Pohl, Andy; Vicent, Guillermo P.; Serra, Francois; Soronellas, Daniel; Castellano, Giancarlo; Wright, Roni; Ballare, Cecilia; Filion, Guillaume; Marti-Renom, Marc A.; Beato, Miguel (Genes & Development, 2014)
      The human genome is segmented into topologically associating domains (TADs), but the role of this conserved organization during transient changes in gene expression is not known. Here we describe the ...
    • MyoD induces ARTD1 and nucleoplasmic poly-ADP-ribosylation during fibroblast to myoblast transdifferentiation 

      Bisceglie, Lavinia; Hopp, Ann-Katrin; Gunasekera, Kapila; Wright, Roni; Le Dily, François; Vidal, Enrique; Dall'Agnese, Alessandra; Caputo, Luca; Nicoletti, Chiara; Puri, Pier Lorenzo; Beato, Miguel; Hottiger, Michael O. (iScience, 2021)
      While protein ADP-ribosylation was reported to regulate differentiation and dedifferentiation, it has so far not been studied during transdifferentiation. Here, we found that MyoD-induced transdifferentiation ...