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Determining the value of two biologic drugs for chronic inflammatory skin diseases: results of a multi-criteria decision analysis
(Springer Nature, 2018)
Background and Objective: Multi-criteria decision analysis (MCDA) is a tool that systematically considers multiple factors relevant to health decision-making. The aim of this study was to use an MCDA ...
High effectiveness of a 14-day concomitant therapy for helicobacter pylori treatment in primary care. An observational multicenter study
(MDPI, 2020)
Background: The current cure rates with triple therapy combining a proton-pump inhibitor, amoxicillin and clarithromycin are unacceptably low. Aims: To evaluate the efficacy of a 14-day concomitant ...
Effects of sedatives and opioids on trigger and cycling asynchronies throughout mechanical ventilation: an observational study in a large dataset from critically ill patients
(Springer Nature, 2019-07-05)
Background: In critically ill patients, poor patient-ventilator interaction may worsen outcomes. Although sedatives are often administered to improve comfort and facilitate ventilation, they can be ...
Interobserver and intertest agreement in telemedicine glaucoma screening with optic disk photos and optical coherence tomography
(MDPI, 2021)
Purpose: To evaluate interobserver and intertest agreement between optical coherence tomography (OCT) and retinography in the detection of glaucoma through a telemedicine program. Methods: A stratified ...
Implication between genetic variants from APOA5 and ZPR1 and NAFLD severity in patients with hypertriglyceridemia
(MDPI, 2021)
Background: Lipid metabolism disorders, especially hypertriglyceridemia (HTG), are risk factors for non-alcoholic fatty liver disease (NAFLD). However, the association between genetic factors related ...
The effectiveness of manual therapy on pain, physical function, and nerve conduction studies in carpal tunnel syndrome patients: a systematic review and meta-analysis
(Springer, 2021)
Aim of the study Systematic review and meta-analysis to assess the efectiveness of manual therapy in improving carpal tunnel syndrome (CTS) symptoms, physical function, and nerve conduction studies. ...
Critical update for the clinical use of L-carnitine analogs in cardiometabolic disorders
(Dove Press, 2011-03-28)
Acetyl-L-carnitine (ALC) and propionyl-L-carnitine (PLC) are two naturally occurring carnitine derivates formed by carnitine acetyltransferase. The beneficial cardiovascular effects of ALC and PLC have ...
The effect of oral citicoline and docosahexaenoic acid on the visual field of patients with glaucoma: a randomized trial
(MDPI, 2022)
The role of nutraceuticals in the treatment of glaucoma remains controversial. The aim of this study was to evaluate the effect of citicoline, vitamin C, and docosahexaenoic acid (DHA) in patients with ...
Does the addition of manual therapy approach to a cervical exercise program improve clinical outcomes for patients with chronic neck pain in short -and mid-term? A randomized controlled trial
(MDPI, 2020)
Chronic neck pain is one of today’s most prevalent pathologies. The International Classification of Diseases categorizes four subgroups based on patients’ associated symptoms. However, this classification ...
The use of next-generation sequencing in the diagnosis of rare inherited anaemias: a joint BSH/EHA good practice paper
(John Wiley & Sons, 2022)
The British Society for Haematology (BSH) produces Good Practice Papers to recommend good practice in areas where there is a limited evidence base but for which a degree of consensus or uniformity is ...