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Changes in lung function in adolescents with substance use disorders: an exploratory study
(Sociedade Brasileira de Pneumologia e Tisiologia, 2023)
Objective: To compare lung function between adolescents with and without substance use disorder (SUD). Methods: This was an observational, cross-sectional exploratory study. The sample consisted of 16 ...
Association of sleep disorders with heart rate variability in children and adolescents with cystic fibrosis
(Zeppelini Publishers, 2022)
Objective: To assess the association of sleep disorders with the findings of heart rate variability (HRV) in children and adolescents with cystic fibrosis (CF). Methods: Cross-sectional study including ...
Variation in nicotine metabolization according to biological factors and type of nicotine consumer
(MDPI, 2023)
This study aims to describe the nicotine metabolite ratio among tobacco smokers and electronic cigarette (e-cigarette) users and nonusers. We analyzed pooled data from a longitudinal and a cross-sectional ...
Differential nasopharyngeal microbiota composition in children according to respiratory health status
(Microbiology Society, 2021)
Acute respiratory infections (ARIs) constitute one of the leading causes of antibiotic administration, hospitalization and death among children <5 years old. The upper respiratory tract microbiota has ...
Related factors to streptococcus pneumoniae invasive infection and clinical manifestations: the potential role of nasopharyngeal microbiome
(Frontiers Media, 2021-04)
Infections of the lower respiratory tract, such as pneumonia, are one of the leading causes of death worldwide. Streptococcus pneumoniae might colonize the upper respiratory tract and is the main ...
Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells
(Springer Nature, 2018)
With a diverse network of substrates, NUDIX hydrolases have emerged as a key family of nucleotide-metabolizing enzymes. NUDT5 (also called NUDIX5) has been implicated in ADP-ribose and 8-oxo-guanine ...
Prenatal stress induces long-lasting effects in lung glucocorticoid receptor gene expression in a sex-dependent manner
(Scientia Medica, 2019)
AIM: Stressful events during pregnancy may influence respiratory system development, resulting in long-term effects in the offspring. However, little is known on its long-lasting effects upon the ...
A social return on investment analysis of improving the management of chronic obstructive pulmonary disease within the spanish national healthcare system
(Dove Press, 2022)
Purpose: To define a set of proposals that would improve the current management of chronic obstructive pulmonary disease (COPD) within the Spanish National Healthcare System (SNHS) from a comprehensive ...
Mechanisms of ventilatory limitation to maximum exercise in children and adolescents with chronic airway diseases
(John Wiley & Sons, 2023)
Introduction: Exercise intolerance is common in chronic airway diseases (CAD), but its mechanisms are still poorly understood. The aim of this study was to evaluate exercise capacity and its association ...
Safety and efficacy of devices delivering Inhaled antibiotics among adults with non-cystic fibrosis bronchiectasis: a systematic review and a network meta-analysis
(MDPI, 2022)
It remains unknown whether the type of aerosol generating device is affecting efficacy and safety among non-cystic fibrosis bronchiectasis (NCFB) adults. The proposal of this network meta-analysis (NMA) ...