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New insights of SF1 neurons in hypothalamic regulation of obesity and diabetes
(MDPI, 2021)
Despite the substantial role played by the hypothalamus in the regulation of energy balance and glucose homeostasis, the exact mechanisms and neuronal circuits underlying this regulation remain poorly ...
Effects of the manual therapy approach of segments C0-1 and C2-3 in the flexion-rotation test in patients with chronic neck pain: a randomized controlled trial
(MDPI, 2021-01)
Background: Flexion-rotation test predominantly measures rotation in C1-2 segment. Restriction in flexion-rotation may be due to direct limitation in C1-2, but also to a premature tightening of the alar ...
Differential nasopharyngeal microbiota composition in children according to respiratory health status
(Microbiology Society, 2021)
Acute respiratory infections (ARIs) constitute one of the leading causes of antibiotic administration, hospitalization and death among children <5 years old. The upper respiratory tract microbiota has ...
Challenges for hospital management in supporting nurses to deliver humanized care
(Wiley, 2021)
Hospitals are paying increasing attention to the delivery of humanized care. The purpose of this study was to explore from the nursing perspective what hospital managers might do to facilitate this. A ...
Biceps femoris activation during hamstring strength exercises: a systematic review
(MDPI, 2021)
Background: The aim of the study was to systematically evaluate the biceps femoris long head activation across cross-sectional hamstring strength exercise studies. Methods: A systematic review design ...
Sonochemical coating of Prussian Blue for the production of smart bacterial-sensing hospital textiles
(Elsevier, 2021-01)
In healthcare facilities, environmental microbes are responsible for numerous infections leading to patient’s health complications and even death. The detection of the pathogens present on contaminated ...
Carnitine palmitoyltransferase 1C negatively regulates the endocannabinoid hydrolase ABHD6 in mice, depending on nutritional status
(John Wiley & Sons, 2021-01)
Background and Purpose: The enzyme α/β‐hydrolase domain containing 6 (ABHD6), a new member of the endocannabinoid system, is a promising therapeutic target against neuronal‐related diseases. However, ...
Role of the NUDT enzymes in breast cancer
(MDPI, 2021)
Despite global research efforts, breast cancer remains the leading cause of cancer death in women worldwide. The majority of these deaths are due to metastasis occurring years after the initial treatment ...
High-dose methylprednisolone pulses for 3 days vs. low-dose dexamethasone for 10 days in severe, non-critical COVID-19: a retrospective propensity score matched analysis
(MDPI, 2021)
Corticosteroids are largely recommended in patients with severe COVID-19. However, evidence to support high-dose methylprednisolone (MP) pulses is not as robust as that demonstrated for low-dose ...
Computational modeling as a tool to investigate PPI: from drug design to tissue engineering
(Frontiers Media S.A., 2021)
Protein-protein interactions (PPIs) mediate a large number of important regulatory pathways. Their modulation represents an important strategy for discovering novel therapeutic agents. However, the ...