Browsing Ciències de la Salut by Title
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Survival benefit of multidisciplinary care in amyotrophic lateral sclerosis in Spain: association with noninvasive mechanical ventilation
(Journal of Multidisciplinary Healthcare, 2019)Purpose: Multidisciplinary care has become the preferred model of care for patients with amyotrophic lateral sclerosis (ALS). It is assumed that the sum of interventions associated with this approach ... -
Susceptibility to severe acute respiratory syndrome coronavirus 2 infection among children and adults: a seroprevalence study of family households in the Barcelona metropolitan region, Spain
(Clinical Infectious Diseases, 2021-06)Background: Susceptibility of children and adults to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and persistence of antibody response to the virus after infection resolution ... -
Syndemic conditions and quality of life in the PISCIS Cohort of people living with HIV in Catalonia and the Balearic Islands: a cross sectional study
(Health and Quality of Life Outcomes, 2023)Background: People living with HIV (PLWH) face structural and psychosocial factors that affect health-related quality of life (HRQoL). We aimed to evaluate how syndemic conditions affected HRQoL in PLWH. ... -
Synthesis and deposition of silver nanoparticles on cp Ti by laser ablation in open air for antibacterial effect in dental implants
(Materials Letters, 2018-07-30)Silver nanoparticles have been synthetized and deposited on cp Ti substrates in one-step process by the use of laser ablation in open air. The nanoparticles are produced by ablating Ag foil using two ... -
A systematic analysis of orphan cyclins reveals CNTD2 as a new oncogenic driver in lung cancer
(2017-08-31)As lung cancer has increased to the most common cause of cancer death worldwide, prognostic biomarkers and efective targeted treatments remain lacking despite advances based on patients’ stratifcation. ... -
Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells
(Nature Communications, 2018)With a diverse network of substrates, NUDIX hydrolases have emerged as a key family of nucleotide-metabolizing enzymes. NUDT5 (also called NUDIX5) has been implicated in ADP-ribose and 8-oxo-guanine ... -
Targeting carnitine palmitoyltransferase 1 isoforms in the hypothalamus: a promising strategy to regulate energy balance
(Journal of Neuroendocrinology, 2023)Tackling the growing incidence and prevalence of obesity urgently requires uncovering new molecular pathways with therapeutic potential. The brain, and in particular the hypothalamus, is a major integrator ... -
Targeting DNA repair defects for precision medicine in prostate cancer
(Current Oncology Reports, 2019)Purpose of Review: Genomic studies of localized and metastatic prostate cancer have identified a high prevalence of clinically actionable alterations including mutations in DNA repair genes. In this ... -
Targeting the Src N-terminal regulatory element in cancer
(Oncotarget, 2023)The signaling pathways displayed by cancer cells are often composed by the same components than the physiological ones, yet the overall result is a pathological deregulation. The non-receptor protein ... -
Task-dependent modulation of the visual sensory thalamus assists visual-speech recognition
(NeuroImage, 2018-09)The cerebral cortex modulates early sensory processing via feed-back connections to sensory pathway nuclei. The functions of this top-down modulation for human behavior are poorly understood. Here, we ... -
Telerehabilitation for balance rehabilitation in the subacute stage of stroke: a pilot controlled trial
(NeuroRehabilitation, 2022)BACKGROUND:Telerehabilitation has been proposed as an effective strategy to deliver post-stroke specific exercise. OBJECTIVE:To assess the effectiveness and feasibility of core stability exercises guided ... -
Temperature and current flow effects of different electrode placement in shoulder capacitive-resistive electric transfer applications: a cadaveric study
(BMC Musculoskeletal Disorders, 2021)Background: Impingement syndrome is currently estimated to represent 60% of all shoulder pain disorders. Capacitive-Resistive electric transfer therapy is aimed to provoke temperature and current flow ... -
Temporal validation of a risk prediction model for breast cancer-related lymphoedema in European population: a retrospective study
(Journal of Advanced Nursing, 2023)Aims: To perform temporal validation of a risk prediction model for breast cancer-related lymphoedema in the European population. Design: Temporal validation of a previously developed prediction model ... -
The actin binding protein profilin 2 is a novel regulator of iron homeostasis
(Blood, 2017)Cellular iron homeostasis is controlled by the iron regulatory proteins (IRPs) 1 and 2 that bind cis-regulatory iron-responsive elements (IRE) on target messenger RNAs (mRNA). We identified profilin 2 ... -
The atypical cyclin CNTD2 promotes colon cancer cell proliferation and migration
(2018-08-07)Colorectal cancer (CRC) is one of the most common cancers worldwide, with 8–10% of these tumours presenting a BRAF (V600E) mutation. Cyclins are known oncogenes deregulated in many cancers, but the role ... -
The critical size is set at a single-cell level by growth rate to attain homeostasis and adaptation
(Nature Communications, 2012-08-21)Budding yeast cells are assumed to trigger Start and enter the cell cycle only after they attain a critical size set by external conditions. However, arguing against deterministic models of cell size ... -
The effectiveness of extracorporeal shock wave therapy for improving upper limb spasticity and functionality in stroke patients: a systematic review and meta-analysis
(Clinical Rehabilitation, 2020)Objective: To assess the effectiveness of Extracorporeal Shock Wave Therapy for reducing spasticity and improving functionality of the upper limb in stroke survivors. Data sources: A systematic review ... -
The effectiveness of extracorporeal shock wave therapy to reduce lower limb spasticity in stroke patients: a systematic review and meta-analysis
(Topics in Stroke Rehabilitation, 2019)Objective: To assess the effectiveness of Extracorporeal Shock Wave Therapy (ESWT) to reduce lower limb spasticity in adult stroke survivors. Data Sources: A systematic review of Medline/Pubmed, CENTRAL, ... -
The effectiveness of finasteride and dutasteride used for 3 years in women with androgenetic alopecia
(Indian Journal of Dermatology, Venereology and Leprology, 2014-11-01)Background: The effectiveness of finasteride and dutasteride in women with androgenetic alopecia has been the subject of debate. Aim: To evaluate the effectiveness of finasteride and dutasteride on ... -
The effects of alcohol and drugs of abuse on maternal nutritional profile during pregnancy
(Nutrients, 2018)The consumption of alcohol and drugs of abuse among pregnant women has experienced a significant increase in the last decades. Suitable maternal nutritional status is crucial to maintain the optimal ...