Soemmerring's rings developed around IOLs, in human donor eyes, can present internal transparent areas
Author
D'Antin, Justin Christopher
Tresserra, Francesc
Barraquer, Rafael I.
Michael, Ralph
Publication date
2022ISSN
1422-0067
Abstract
Soemmerring’s rings consist of a ring of lens epithelial derived cells that grow along the periphery of an aphakic lens capsule, or around an intraocular lens. These rings when visualized frontally, appear opaque, however, in some cases the cells that compose these rings are organized in the same fashion as those in normal transparent adult lenses. Thus, our purpose was to test whether any part of the adult Soemmerring’s ring could be transparent and how this related to morphological factors. To study this, 16 Soemmerring’s rings were extracted from donor eye globes. After imaging, they were thickly sectioned sagittally in order to analyze the degrees of transparency of different areas. All samples were also histologically analyzed using alpha smooth muscle actin, Vimentin, wheat germ agglutinin and DAPI. Our results showed that many samples had some transparent areas, mostly towards the center of their cross-section. Of the factors that we analyzed, only lens fiber organization at the bow region and an increased area of mature lens fiber cells had a significant relation to the degree of transparency at the center. Thus, we can conclude that as Soemmerring’s rings mature, they can develop organized and transparent areas of lens cells.
Document Type
Article
Document version
Published version
Language
English
Subject (CDU)
616.3 - Pathology of the digestive system. Complaints of the alimentary canal
Keywords
Anell de Soemmerring
LIO
Lent
Histologia
Anillo de Soemmerring
LIO
Lente
Histología
Soemmerring’s ring
IOL
Lens
Histology
Pages
14
Publisher
MDPI
Collection
23; 21
Is part of
International Journal of Molecular Sciences
Citation
D'Antin, Justin Christopher; Tresserra, Francesc; Barraquer, Rafael I. [et al.]. Soemmerring's rings developed around IOLs, in human donor eyes, can present internal transparent areas. International Journal of Molecular Sciences, 2022, 23(21), 13294. Disponible en: <https://www.mdpi.com/1422-0067/23/21/13294>. Fecha de acceso: 5 feb. 2024. DOI: 10.3390/ijms232113294
This item appears in the following Collection(s)
- Ciències de la Salut [738]
Rights
© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).