dc.contributor.author | Donadio, Márcio V.F. | |
dc.contributor.author | De Souza, Guilherme C. | |
dc.contributor.author | Tiecher, Gabriele | |
dc.contributor.author | Heinzmann-Filho, João P. | |
dc.contributor.author | Paim, Taísa F. | |
dc.contributor.author | Hommerding, Patrícia X. | |
dc.contributor.author | Marosticaf, Paulo J.C. | |
dc.date.accessioned | 2022-04-01T14:36:45Z | |
dc.date.available | 2022-04-01T14:36:45Z | |
dc.date.issued | 2013 | |
dc.identifier.citation | Donadio, Márcio V.F.; De Souza, Guilherme C.; Tiecher, Gabriele [et al.]. Bone mineral density, pulmonary function, chronological age, and age at diagnosis in children and adolescents with cystic fibrosis. Jornal de Pediatria, 2013, 89(2), p. 151-157. Disponible en: <https://www.sciencedirect.com/science/article/pii/S0021755713000259?via%3Dihub>. Fecha de acceso: 1 abr. 2022. DOI: 10.1016/j.jped.2013.03.008 | ca |
dc.identifier.issn | 0021-7557 | ca |
dc.identifier.uri | http://hdl.handle.net/20.500.12328/3207 | |
dc.description.abstract | Objective: To assess bone mineral density in patients with cystic fibrosis (CF), and to correlate it with possible intervening variables. Methods: Children and adolescents diagnosed with CF, aged 6 to 18 years, followed at the outpatient clinic were included in the study. First, demographic data were collected and, subsequently, patients underwent a spirometric test. All patients answered the Cystic Fibrosis Quality of Life Questionnaire (CFQ) and underwent the six-minute walk test (6MWT) and bone densitometry (DXA). Results: A total of 25 CF patients were included, of which 56% were males. The mean age was 12.3±3.4 years; mean height was 149.2±14.4 cm; and mean weight was 44.4±13.9 kg. Most results on pulmonary function and bone mineral density (BMD) were within normal limits. The mean forced expiratory volume in one second (FEV) was 92.5±23.6 (% of predicted), mean forced vital capacity (FVC) was 104.4±21.3 (% of predicted), and1 mean BMD z-score was 0.1±1.0. BMD was moderately correlated with FEV (r = 0.43, p = 0.03) and FVC (r = 0.57, p = 0.003). Regarding chronological age and age at diagnosis, a moderate and inverse correlation was also found (r = −0.55, p = 0.004; r = −0.57, p = 0.003, respectively). However, no significant correlations were found with the data from CFQ, 6MWT, and body mass index. Conclusion: Most patients had BMD within normal limits and presented a positive correlation with pulmonary function, as well as a negative correlation with chronological age and age at diagnosis. | en |
dc.format.extent | 7 | ca |
dc.language.iso | eng | ca |
dc.publisher | Elsevier | ca |
dc.relation.ispartof | Jornal de Pediatria | ca |
dc.relation.ispartofseries | 89;2 | |
dc.rights | Under a Creative Commons license. | ca |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.subject.other | Densitat mineral òssia | ca |
dc.subject.other | Fibrosi quística | ca |
dc.subject.other | Funció pulmonar | ca |
dc.subject.other | Densidad mineral ósea | es |
dc.subject.other | Fibrosis quística | es |
dc.subject.other | Función pulmonar | es |
dc.subject.other | Bone mineral density | en |
dc.subject.other | Cystic fibrosis | en |
dc.subject.other | Pulmonary function | en |
dc.title | Bone mineral density, pulmonary function, chronological age, and age at diagnosis in children and adolescents with cystic fibrosis | en |
dc.title.alternative | Densidade mineral óssea, função pulmonar, idade cronológica e idade de diagnóstico em crianças e adolescentes com fibrose cística | pt |
dc.type | info:eu-repo/semantics/article | ca |
dc.description.version | info:eu-repo/semantics/publishedVersion | ca |
dc.rights.accessLevel | info:eu-repo/semantics/openAccess | |
dc.embargo.terms | cap | ca |
dc.subject.udc | 61 | ca |
dc.subject.udc | 616.7 | ca |
dc.identifier.doi | https://dx.doi.org/10.1016/j.jped.2013.03.008 | ca |