Browsing Ciències Bàsiques by Subject "Regulació gènica"

Now showing items 1-2 of 2

    • ADP-ribose–derived nuclear ATP synthesis by NUDIX5 is required for chromatin remodeling 

      Wright, Roni; LeDily, Francois; Soronellas, Daniel; Pohl, Andy; Bonet, Jaume; Nacht, A. S.; Vicent, Guillermo Pablo; Wierer, Michael; Oliva, Baldo; Beato, Miguel (Science, 2016)
      Key nuclear processes in eukaryotes, including DNA replication, repair, and gene regulation, require extensive chromatin remodeling catalyzed by energy-consuming enzymes. It remains unclear how the ATP ...

    • ATP, Mg2+, nuclear phase separation, and genome accessibility 

      Wright, Roni; Le Dily, François; Beato, Miguel (Trends in Biochemical Sciences, 2019)
      Misregulation of the processes controlling eukaryotic gene expression can result in disease. Gene expression is influenced by the surrounding chromatin; hence the nuclear environment is also of vital ...