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dc.contributor.authorPaloni, Giulia
dc.contributor.authorSilecchia, Valeria
dc.contributor.authorBerti, Irene
dc.contributor.authorTagarelli, Arianna
dc.contributor.authorMazzoni, Elisa
dc.contributor.authorLambertini, Andrea
dc.contributor.authorValerio, Enrico
dc.contributor.authorGrimalt, Ramon
dc.contributor.authorCutrone, Mario
dc.date.accessioned2021-05-05T17:40:40Z
dc.date.available2021-05-05T17:40:40Z
dc.date.issued2019-12
dc.identifier.citationPaloni, Giulia; Silecchia, Valeria; Berti, Irene [et al.]. Bullous henoch-schönlein purpura: a case series. Journal of Respiratory Research, 2019, 4(2), p. 191-184. Disponible en: <http://www.ghrnet.org/index.php/jdr/article/view/2733>. Fecha de acceso: 5 may. 2021. DOI: :10.17554/j.issn.2413-8223.2019.04.46-7ca
dc.identifier.issn2413-8223ca
dc.identifier.urihttp://hdl.handle.net/20.500.12328/2522
dc.description.abstractHenoch-Schönlein purpura (HSP) represents the most common vasculitis in children. Typically, HSP manifests with palpable purpura and edema, usually following an urticarial or erythematous maculopapular eruption. Bullous HSP represents an uncommon presentation of “classic” HSP, exhibited by only 2% of affected children. We here present three cases of bullous HSP. This variant seems due to an excess of production of neutrophilic matrix metalloproteinase-9, a lytic enzyme that degrades basement membrane components, eventually leading to dermoepidermal detachment and blister formation. Notably, American College of Rheumatology (ACR), Paediatric Rheumatology European Society (PRES), European League against Rheumatism (EULAR), and Paediatric Rheumatology INternational Trials Organization (PRINTO) do not encompass blisters and/or bullae into HSP classification criteria. Outcome of bullous HSP does not differ from “classic” purpuric HSP. The former, however, demands special care measures: local pain control, topic antibiotic therapy, and protective dressings over areas of open or blistered skin.en
dc.format.extent4ca
dc.language.isoengca
dc.publisherACT Publishing Group Limitedca
dc.relation.ispartofJournal of Respiratory Researchca
dc.relation.ispartofseries4;2
dc.rightsThis article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work noncommercially, and license their derivative works on different terms, provided the original work is properly cited and the use is noncommercial. See: http://creativecommons.org/licenses/by-nc/4.0/en
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/
dc.subject.otherDermatologiaca
dc.subject.otherPediatriaca
dc.subject.otherVasculitisca
dc.subject.otherFerides i lesionsca
dc.subject.otherDermatologíaes
dc.subject.otherPediatríaes
dc.subject.otherVasculitises
dc.subject.otherHeridas y lesioneses
dc.subject.otherDermatologyen
dc.subject.otherPediatricsen
dc.subject.otherVasculitisen
dc.subject.otherWounds and injuriesen
dc.titleBullous henoch-schönlein purpura: a case seriesen
dc.typeinfo:eu-repo/semantics/articleca
dc.description.versioninfo:eu-repo/semantics/publishedVersionca
dc.rights.accessLevelinfo:eu-repo/semantics/openAccess
dc.embargo.termscapca
dc.subject.udc61ca
dc.identifier.doihttp://dx.doi.org/10.17554/j.issn.2413-8223.2019.04.46-7ca


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This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work noncommercially, and license their derivative works on different terms, provided the original work is properly cited and the use is noncommercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by-nc/4.0/