Evaluation of bone loss in antibacterial coated dental implants: an experimental study in dogs
Autor/a
Godoy Gallardo, Maria
Manzanares-Céspedes, Maria Cristina
Sevilla Sánchez, Pablo
Nart Molina, José
Manzanares, Norberto
Manero Planella, José María
Gil Mur, Francisco Javier
Boyd, Steven K.
Rodríguez, Daniel
Data de publicació
2016-12ISSN
0928-4931
Resum
The aim of this study was to evaluate the in vivo effect of antibacterial modified dental implants in the first stages of peri-implantitis. Thirty dental implants were inserted in the mandibular premolar sites of 5 beagle dogs. Sites were randomly assigned to Ti (untreated implants, 10 units), Ti_Ag (silver electrodeposition treatment, 10 units), and Ti_TSP (silanization treatment, 10 units). Coated implants were characterized by scanning electron microscopy, interferometry and X-ray photoelectron spectroscopy. Two months after implant insertion, experimental peri-implantitis was initiated by ligature placement. Ligatures were removed 2 months later, and plaque formation was allowed for 2 additional months. Clinical and radiographic analyses were performed during the study. Implant-tissue samples were prepared for micro computed tomography, backscattered scanning electron microscopy, histomorphometric and histological analyses and ion release measurements. X-ray, SEM and histology images showed that vertical bone resorption in treated implants was lower than in the control group (P < 0.05). This effect is likely due to the capacity of the treatments to reduce bacteria colonization on the implant surface. Histological analysis suggested an increase of peri-implant bone formation on silanized implants. However, the short post-ligature period was not enough to detect differences in clinical parameters among implant groups. Within the limits of this study, antibacterial surface treatments have a positive effect against bone resorption induced by peri-implantitis.
Tipus de document
Article
Versió del document
Versió acceptada
Llengua
Anglès
Matèries (CDU)
616.3 - Patologia de l'aparell digestiu. Odontologia
Paraules clau
Implants dentals
Gossos
Bacteris
Implantes dentales
Perros
Bacterias
Dental implants
Dogs
Bacteria
Pàgines
31
Publicat per
Elsevier
Col·lecció
69;
Publicat a
Materials Science and Engineering: C
Citació
Godoy-Gallardo, Maria; Manzanares-Céspedes, Maria Cristina; Sevilla, Pablo [et al.]. Evaluation of bone loss in antibacterial coated dental implants: an experimental study in dogs. Materials Science and Engineering: C, 2016, 69, p. 538-545. Disponible en: <https://www.sciencedirect.com/science/article/abs/pii/S0928493116306944?via%3Dihub>. Fecha de acceso: 28 jun. 2020. DOI: 10.1016/j.msec.2016.07.020
Número de l'acord de la subvenció
info:eu-repo/grantAgreement/ES/1PE/MAT2009-12547
info:eu-repo/grantAgreement/MINECO/6PN/MAT2012-30706
Aquest element apareix en la col·lecció o col·leccions següent(s)
- Ciències de la Salut [725]
Drets
© 2016 Elsevier B.V. All rights reserved.