Installing multifunctionality on titanium with RGD-decorated polyurethane-polyurea roxithromycin loaded nanoparticles: toward new osseointegrative therapies

Rocas, Pau; Hoyos Nogués, Mireia; Rocas, Josep; Manero Planella, José María; Gil Mur, Francisco Javier; Albericio Palomera, Fernando; Mas Moruno, Carlos

dc.contributor.author	Rocas, Pau
dc.contributor.author	Hoyos Nogués, Mireia
dc.contributor.author	Rocas, Josep
dc.contributor.author	Manero Planella, José María
dc.contributor.author	Gil Mur, Francisco Javier
dc.contributor.author	Albericio Palomera, Fernando
dc.contributor.author	Mas Moruno, Carlos
dc.date.accessioned	2020-06-17T15:21:23Z
dc.date.available	2020-06-17T15:21:23Z
dc.date.issued	2015
dc.identifier.citation	Rocas, Pau; Hoyos Nogués, Mireia; Rocas, Josep [et al.]. Installing multifunctionality on titanium with RGD-decorated polyurethane-polyurea roxithromycin loaded nanoparticles: toward new osseointegrative therapies. Advanced Healthcare Materials, 2015, 4(13), p. 1-5. Disponible en: <https://onlinelibrary.wiley.com/doi/full/10.1002/adhm.201500245>. Fecha de acceso: 17 jun. 2020. DOI: 10.1002/adhm.201500245	ca
dc.identifier.issn	2192-2640	ca
dc.identifier.uri	http://hdl.handle.net/20.500.12328/1588
dc.description	The authors thank the Spanish Government for financial support through Project No. MAT2012–30706, cofunded by the European Union through European Regional Development Funds, and the Government of Catalonia (SGR2009 1039). C.M.-M. thanks the support of the Secretary for Universities and Research of the Ministry of Economy and Knowledge of the Government of Catalonia (2011-BP-B-00042) and the People Programme (Marie Curie Actions) of the European Union’s Seventh Framework Programme (FP7-PEOPLE-2012-CIG, REA Grant Agreement No. 321985). P.R., J.R., and F.A. thank the Spanish Government (MICINN) for fi nancial support into the INNPACTO Project No. IPT-090000–2010–1 (Polysfera).	en
dc.description.abstract	A novel class of polyurethane-polyurea nanoparticles (PUUa NPs) to install multifunctionality on biomaterials is presented. Biofunctionalization of titanium with roxithromycin loaded RGD-decorated PUUa NPs results in an outstanding improvement of osteoblast adhesion and strong suppression of bacterial attachment. This strategy represents a powerful approach to enhance the osseointegration of implant materials.	ca
dc.format.extent	5	ca
dc.language.iso	eng	ca
dc.publisher	Wiley	ca
dc.relation.ispartof	Advanced Healthcare Materials	ca
dc.relation.ispartofseries	4;13
dc.rights	This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifi cations or adaptations are made.	ca
dc.rights.uri	https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.other	Titani	ca
dc.subject.other	Materials biomèdics
dc.subject.other	Implants
dc.subject.other	Materials nanoestructurats
dc.subject.other	Pèptids
dc.subject.other	Titanio
dc.subject.other	Materiales biomédicos
dc.subject.other	Implantes
dc.subject.other	Materiales nanoestructurados
dc.subject.other	Péptidos
dc.subject.other	Titanium
dc.subject.other	Biomedical materials
dc.subject.other	Implants
dc.subject.other	Nanostructured materials
dc.subject.other	Peptides
dc.title	Installing multifunctionality on titanium with RGD-decorated polyurethane-polyurea roxithromycin loaded nanoparticles: toward new osseointegrative therapies	ca
dc.type	info:eu-repo/semantics/article	ca
dc.description.version	info:eu-repo/semantics/acceptedVersion	ca
dc.embargo.terms	cap	ca
dc.relation.projectID	info:eu-repo/grantAgreement/ES/MINECO/6PN/MAT2012-30706
dc.relation.projectID	info:eu-repo/grantAgreement/EC/FP7/321985
dc.subject.udc	61	ca
dc.identifier.doi	https://dx.doi.org/10.1002/adhm.201500245	ca