Cost-minimization analysis favours intravenous ferric carboxymaltose over ferric sucrose or oral iron as preoperative treatment in patients with colon cancer and iron deficiency anaemia
Author
Calvet, Xavier
Gené Tous, Emilio Miguel
Ruíz, Miquel Àngel
Figuerola, Ariadna
Villoria, Albert
Cucala, Mercedes
Mearin, Fermín
Delgado, Salvadora
Calleja, Jose Luis
Publication date
2016ISSN
0928-7329
Abstract
Background: Ferric Carboxymaltose (FCM), Iron Sucrose (IS) and Oral Iron (OI) are alternative treatments for preoper-ative anaemia. Objective: To compare the cost implications, using a cost-minimization analysis, of three alternatives: FCM vs. IS vs. OIfor treating iron-deficient anaemia before surgery in patients with colon cancer. Methods: Data from 282 patients with colorectal cancer and anaemia were obtained from a previous study. One hundred andeleven received FCS, 16 IS and 155 OI. Costs of intravenous iron drugs were obtained from the Spanish Regulatory Agency. Direct and indirect costs were obtained from the analytical accounting unit of the Hospital. In the base case mean costs perpatient were calculated. Sensitivity analysis and probabilistic Monte Carlo simulation were performed. Results: Total costs per patient were 1827R© in the FCM group, 2312R© in the IS group and 2101R©i n the OI group. Costsavings per patient for FCM treatment were 485R© compared to IS and 274R© compared to OI. A Monte Carlo simulationfavoured the use of FCM in 84.7% and 84.4% of simulations when compared to IS and OI, respectively. Conclusions: FCM infusion before surgery reduced costs in patients with colon cancer and iron-deficiency anaemia whencompared with OI and IS.
Document Type
Article
Document version
Accepted version
Language
English
Subject (CDU)
61 - Medical sciences
Keywords
Tumors
Còlon -- Càncer
Anèmia
Ferro -- Metabolisme
Medicació
Tumores
Colon -- Cáncer
Anemia
Hierro en el organismo
Medicación
Tumors
Colon cancer
Anemia
Iron -- Metabolism
Medication
Pages
10
Publisher
IOS Press
Collection
24; 1
Is part of
Technology and Health Care
Citation
Calvet, Xavier; Gené Tous, Emilio Miguel; Ruíz, Miquel Àngel [et al.]. Cost-minimization analysis favours intravenous ferric carboxymaltose over ferric sucrose or oral iron as preoperative treatment in patients with colon cancer and iron deficiency anaemia. Technology and Health Care, 2016, 24(1), p. 11-120. Disponible en: <https://content.iospress.com/articles/technology-and-health-care/thc1074>. Fecha de acceso: 26 may. 2020. DOI: 10.3233/THC-151074.
This item appears in the following Collection(s)
- Ciències de la Salut [741]
Rights
© 2016 – IOS Press and the authors. All rights reserved. This article is published online with Open Access and distributed under the terms of the Creative Commons Attribution Non-Commercial License.
Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by-nc/3.0/