Ciències de la Salut: Agregados recientemente
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Proactive and systematic multidimensional needs assessment in patients with advanced cancer approaching palliative care: a study protocol
(BMJ Open, 2020)Introduction The benefits of palliative care rely on how healthcare professionals assess patients’ needs in the initial encounter/s; crucial to the design of a personalised therapeutic plan. However, ... -
Proteasomal-mediated degradation of AKAP150 accompanies AMPAR endocytosis during cLTD
(eNeuro, 2020-03-23)The number and function of synaptic AMPA receptors (AMPARs) tightly regulates excitatory synaptic transmission. Current evidence suggests that AMPARs are inserted into the postsynaptic membrane during ... -
Wear in two cases of ceramic on ceramic total hip arthroplasty after 30 years follow up
(Biomedical Journal of Scientific & Technical Research, 2018)Background: Ceramic-on-ceramic (CoC) bearings have been in use in total hip replacement (THR) for more than 40 years, with excellent long-term survivorship but concerns over the ceramic-on-ceramic ... -
Sensing of nutrients by CPT1C regulates late endosome/lysosome anterograde transport and axon growth
(eLife, 2019)Anterograde transport of late endosomes or lysosomes (LE/Lys) is crucial for proper axon growth. However, the role of energetic nutrients has been poorly explored. Malonyl-CoA is a precursor of fatty ... -
Effects of autologous adipose-derived regenerative stem cells administered at the time of anterior cruciate ligament reconstruction on knee function and graft healing
(Journal of Orthopaedic Surgery, 2019)Purpose: To compare the healing and clinical outcomes of anterior cruciate ligament (ACL) reconstruction between patients with or without intraoperative administration of adipose-derived regenerative ... -
Cost-minimization analysis favours intravenous ferric carboxymaltose over ferric sucrose or oral iron as preoperative treatment in patients with colon cancer and iron deficiency anaemia
(Technology and Health Care, 2016)Background: Ferric Carboxymaltose (FCM), Iron Sucrose (IS) and Oral Iron (OI) are alternative treatments for preoper-ative anaemia. Objective: To compare the cost implications, using a cost-minimization ... -
Síndrome de muerte súbita del lactante: ¿siguen las familias las recomendaciones?
(Anales de Pediatría, 2020-04)Introducción: La postura en decúbito prono al dormir es el principal factor de riesgo modificable conocido para el síndrome de muerte súbita del lactante (SMSL). Existen otras recomendaciones respecto ... -
Structural (betaalpha) 8 TIM barrel model of 3-hydroxy-3-methylglutaryl-coenzyme A lyase
(Journal of Biological Chemistry, 2003)This study describes three novel homozygous missense mutations (S75R, S201Y, and D204N) in the 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) lyase gene, which caused 3-hydroxy-3-methylglutaric aciduria in ... -
Hypothalamic AMPK-ER Stress-JNK1 axis mediates the central actions of thyroid hormones on energy balance
(Cell Metabolism, 2017-07)Thyroid hormones (THs) act in the brain to modulate energy balance. We show that central triiodothyronine (T3) regulates de novo lipogenesis in liver and lipid oxidation in brown adipose tissue (BAT) ... -
Socio-environmental correlates of physical activity in patients with chronic obstructive pulmonary disease (COPD)
(Thorax, 2017)Background. Study of the causes of the reduced levels of physical activity in patients with COPD has been scarce and limited to biological factors. Aim: To assess the relationship between novel ... -
Study on the use of 3‐aminopropyltriethoxysilane and 3‐chloropropyltriethoxysilane to surface biochemical modification of a novel low elastic modulus Ti–Nb–Hf alloy
(Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2014-06-09)A biocompatible new titanium alloy Ti–16Hf–25Nb with low elastic modulus (45 GPa) and the use of short bioadhesive peptides derived from the extracellular matrix have been studied. In terms of cell ... -
Surface immobilization and bioactivity of TGF-ß1 inhibitor peptides for bone implant applications
(Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2016-02-01)TGF-ß1 is the most related cytokine with the production of fibrotic tissue. It plays an important role on the production of collagen by fibroblasts and other types of cells. The inhibition of this ... -
Mechanical and microstructural characterization of new nickel-free low modulus beta-type titanium wires during thermomechanical treatments
(Materials Science and Engineering: A, 2015-06-11)NiTi alloy is the only practical shape memory alloy (SMA) in biomedical use because of its excellent mechanical stability and functionality. However, it is estimated that between 4.5% and 28.5% of the ... -
Surface guidance of stem cell behavior: chemically tailored co-presentation of integrin-binding peptides stimulates osteogenic differentiation in vitro and bone formation in vivo
(Acta Biomaterialia, 2016-10-01)Surface modification stands out as a versatile technique to create instructive biomaterials that are able to actively direct stem cell fate. Chemical functionalization of titanium has been used in this ... -
Silver deposition on titanium surface by electrochemical anodizing process reduces bacterial adhesion of Streptococcus sanguinis and Lactobacillus salivarius
(Clinical Oral Implants Research, 2014-05-30)Objectives: The aim of this study was to determine the antibacterial properties of silver‐doped titanium surfaces prepared with a novel electrochemical anodizing process. Material and methods: Titanium ... -
Mechanical and physicochemical characterization along with biological interactions of a new Ti25Nb21Hf alloy for bone tissue engineering
(Journal of Biomaterials Applications, 2015-03-23)Nowadays, one of the main challenges in metal implants for bone substitution is the achievement of an elastic modulus close to that of human cortical bone as well as to provide an adequate interaction ... -
Determination of fluid leakages in the different screw-retained implant-abutment connections in a mechanical artificial mouth
(Journal of Materials Science: Materials in Medicine, 2015-07-15)This study shows the potential risk of microfiltration between two different types of implant-abutment connections screwed at 45 Ncm: external and internal. For the first time the use of a mechanical ... -
Impedimetric antimicrobial peptide-based sensor for the early detection of periodontopathogenic bacteria
(Biosensors and Bioelectronics, 2016-12-15)Peri-implantitis, an inflammation caused by biofilm formation, constitutes a major cause of implant failure in dentistry. Thus, the detection of bacteria at the early steps of biofilm growth represents ... -
Development of tantalum scaffold for orthopaedic applications produced by space-holder method
(Materials & Design, 2015-10-15)In the present study, production of tantalum porous scaffolds using the space holder technique was performed. The effect of size and content of sodium chloride particles, used as space holder, as well ... -
Antibiotic-loaded polypropylene surgical meshes with suitable biological behaviour by plasma functionalization and polymerization
(Biomaterials, 2015-12)Hernia repair is one of the most common operations in general surgery, and its associated complications typically relate to infections, among others. The loading of antibiotics to surgical meshes to ...