Ciències de la Salut: Agregados recientemente
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Complete loss of EPCAM immunoexpression identifies EPCAM deletion carriers in MSH2-negative colorectal neoplasia
(MDPI, 2020)The use of epithelial cell adhesion molecule (EPCAM) immunohistochemistry (IHC) is not included in the colorectal cancer (CRC) screening algorithm to detect Lynch syndrome (LS) patients. The aim of the ... -
Word frequency cues word order in adults: cross-linguistic evidence
(Frontiers in Psychology, 2013-10-02)One universal feature of human languages is the division between grammatical functors and content words. From a learnability point of view, functors might provide entry points or anchors into the syntactic ... -
Oscillation encoding of individual differences in speech perception
(PLoS One, 2014-07-03)Individual differences in second language (L2) phoneme perception (within the normal population) have been related to speech perception abilities, also observed in the native language, in studies assessing ... -
Electrophysiological correlates of second-language syntactic processes are related to native and second language distance regardless of age of acquisition
(Frontiers in Psychology, 2016-02-12)In the present study, we investigate how early and late L2 learners process L2 grammatical traits that are either present or absent in their native language (L1). Thirteen early (AoA = 4 years old) and ... -
Liver CPT1A gene therapy reduces diet‐induced hepatic steatosis in mice and highlights potential lipid biomarkers for human NAFLD
(Federation of American Societies for Experimental Biology, 2020)The prevalence of nonalcoholic fatty liver disease (NAFLD) has increased drastically due to the global obesity pandemic but at present there are no approved therapies. Here, we aimed to revert high‐fat ... -
Humo de tercera mano y otros retos del control del tabaquismo en población pediátrica
(Anales de Pediatría, 2020) -
Knowledge management for systems biology a general and visually driven framework applied to translational medicine
(BMC Systems Biology, 2011)Background: To enhance our understanding of complex biological systems like diseases we need to put all of the available data into context and use this to detect relations, pattern and rules which allow ... -
A truncated form of IKKa is responsible for specific nuclear IKK activity in colorectal cancer
(Cell Reports, 2012-10-25)Nuclear IKKα regulates gene transcription by phosphorylating specific substrates and has been linked to cancer progression and metastasis. However, the mechanistic connection between tumorigenesis and ... -
Simulation methods with extended stability for stiff biochemical Kinetics
(BMC Systems Biology, 2010)Background: With increasing computer power, simulating the dynamics of complex systems in chemistry and biology is becoming increasingly routine. The modelling of individual reactions in (bio)chemical ... -
Antiretroviral therapy suppressed participants withlow CD4RT-cell counts segregate according toopposite immunological phenotypes
(AIDS, 2016-09)Background:The failure to increase CD4þT-cell counts in some antiretroviral therapysuppressed participants (immunodiscordance) has been related to perturbed CD4þT-cell homeostasis and impacts clinical ... -
Surgical management for refractory bleb dysesthesia
(Journal of Ophthalmology, 2020-08)Purpose. To present long-term results of modified bleb-limiting conjunctivoplasty as a successful treatment for intractable bleb dysesthesia and to review the literature on the surgical management of ... -
Real-world epidemiology of potassium derangements among chronic cardiovascular, metabolic and renal conditions: a population-based analysis
(Clinical Epidemiology, 2020)Background: The aims of the present analysis are to estimate the prevalence of five key chronic cardiovascular, metabolic and renal conditions at the population level, the prevalence of renin–angioten ... -
Validity and reliability of the satel 40 Hz stabilometric force platform for measuring quiet stance and dynamic standing balance in healthy subjects
(International Journal of Environmental Research and Public Health, 2020)Background: A force platform must have validity and reliability for optimal use. The objective of this study was to analyze the validity and the reliability of the Satel 40 Hz stabilometric force platform. ... -
Development and validation of a sample entropy-based method to identify complex patient-ventilator interactions during mechanical ventilation
(Scientific Reports, 2020)Patient-ventilator asynchronies can be detected by close monitoring of ventilator screens by clinicians or through automated algorithms. However, detecting complex patient-ventilator interactions (CP-VI), ... -
Sensing of nutrients by CPT1C controls SAC1 activity to regulate AMPA receptor trafficking
(Journal of Cell Biology, 2020-09)Carnitine palmitoyltransferase 1C (CPT1C) is a sensor of malonyl-CoA and is located in the ER of neurons. AMPA receptors (AMPARs) mediate fast excitatory neurotransmission in the brain and play a key ... -
Lower admission blood pressure as an independent predictor of 1-year mortality in elderly patients experiencing a first hospitalization for acute heart failure
(Hellenic Journal of Cardiology, 2019)Background: Systolic blood pressure (SBP) is an acknowledged prognostic factor in patients with heart failure (HF). Admission SBP should be a risk factor for 1-year mortality even in elderly patients ... -
Effect of different implant designs on strain and stress distribution under non-axial loading: a three-dimensional finite element analysis
(International Journal of Environmental Research and Public Health, 2020)Implant design evolved alongside the development of implant therapy. The purpose of this finite element analysis (FEA) study was to analyze the influence of different implant designs on the stress and ... -
Platelet-rich plasma and its use for cicatricial and non-cicatricial alopecias: a narrative review
(Dermatology and Therapy, 2020-06)The concept and description of platelet-rich plasma (PRP) started in the field of hematology and is being extensively used in other fields of medicine. Interest in the application of PRP has been ... -
Reconfigurable multiplexed point of care system for monitoring type 1 diabetes patients
(Biosensors and Bioelectronics, 2019-07)At the point of care (POC), on-side clinical testing allows fast biomarkers determination even in resource-limited environments. Current POC systems rely on tests selective to a single analyte or complex ... -
CPT1c is localized in endoplasmic reticulum of neurons and has carnitine palmitoyltransferase activity
(Journal of Biological Chemistry, 2008)CPT1c is a carnitine palmitoyltransferase 1 (CPT1) isoform that is expressed only in the brain. The enzyme has recently been localized in neuron mitochondria. Although it has high sequence identity with ...