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A truncated form of IKKa is responsible for specific nuclear IKK activity in colorectal cancer
(Elsevier, 2012-10-25)
Nuclear IKKα regulates gene transcription by phosphorylating specific substrates and has been linked to cancer progression and metastasis. However, the mechanistic connection between tumorigenesis and ...
Expression of oncogenic drivers in 3D cell culture depends on nuclear ATP synthesis by NUDT5
(MDPI, 2019)
The growth of cancer cells as oncospheres in three-dimensional (3D) culture provides a robust cell model for understanding cancer progression, as well as for early drug discovery and validation. We have ...
Hormone-control regions mediate steroid receptor–dependent genome organization
(Cold Spring Harbor Laboratory Press, 2019)
In breast cancer cells, some topologically associating domains (TADs) behave as hormonal gene regulation units, within which gene transcription is coordinately regulated in response to steroid hormones. ...
A mini review focused on the proangiogenic role of silicate ions released from silicon-containing biomaterials
(Journal of Tissue Engineering, 2017-04-06)
Angiogenesis is considered an important issue in the development of biomaterials for the successful regeneration of tissues including bone. While growth factors are commonly used with biomaterials to ...