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Effects of using the surgical mask and FFP2 during the 6-min walking test. A randomized controlled trial
(International Journal of Environmental Research and Public Health, 2021)
During the COVID-19 pandemic, the use of masks has been recommended as a containment measure. The mask is a hindrance to normal breathing that causes discomfort. This could put more work on the respiratory ...
Effects of a short-term resistance-training program on heart rate variability in children with cystic fibrosis: a randomized controlled trial
(Frontiers in Physiology, 2021)
Background: Cystic fibrosis (CF) affects the autonomic nervous system (ANS) and exercise in healthy children modulates the interaction between sympathetic and parasympathetic activity. This study aimed ...
Related factors to streptococcus pneumoniae invasive infection and clinical manifestations: the potential role of nasopharyngeal microbiome
(Frontiers in Medicine, 2021-04)
Infections of the lower respiratory tract, such as pneumonia, are one of the leading causes of death worldwide. Streptococcus pneumoniae might colonize the upper respiratory tract and is the main ...
Association of sleep disorders with heart rate variability in children and adolescents with cystic fibrosis
(Sociedade de Pediatria de São Paulo, 2022)
Objective: To assess the association of sleep disorders with the findings of heart rate variability (HRV) in children and adolescents with cystic fibrosis (CF). Methods: Cross-sectional study including ...
Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells
(Nature Communications, 2018)
With a diverse network of substrates, NUDIX hydrolases have emerged as a key family of nucleotide-metabolizing enzymes. NUDT5 (also called NUDIX5) has been implicated in ADP-ribose and 8-oxo-guanine ...
Fructose-1,6-bisphosphate prevents pulmonary fibrosis by regulating extracellular matrix deposition and inducing phenotype reversal of lung myofibroblasts
(PLoS ONE, 2019)
Pulmonary fibrosis (PF) is the result of chronic injury where fibroblasts become activated and secrete large amounts of extracellular matrix (ECM), leading to impaired fibroblasts degradation followed ...
Apoyo a la regulación de fumar en el interior de vehículos privados y espacios públicos al aire libre
(Revista Española de Salud Pública, 2019)
Fundamentos: Conocer el apoyo a la regulación del consumo de tabaco es una pieza clave para avanzar en las políticas de control del tabaquismo y reducir la exposición pasiva al tabaco. El objetivo de ...
A systematic analysis of orphan cyclins reveals CNTD2 as a new oncogenic driver in lung cancer
(2017-08-31)
As lung cancer has increased to the most common cause of cancer death worldwide, prognostic
biomarkers and efective targeted treatments remain lacking despite advances based on patients’
stratifcation. ...
Modified shuttle test distance correlates with peak oxygen uptake in children and adolescents with severe therapy-resistant asthma
(Frontiers in Physiology, 2019)
Introduction: Several tests may be used to assess exercise intolerance in severe therapy-resistant asthma (STRA), including the gold standard cardiopulmonary exercise test (CPET) and the modified shuttle ...
Secondhand exposure to aerosol from electronic cigarettes: pilot study of assessment of tobacco-specific nitrosamine (NNAL) in urine
(Gaceta Sanitaria, 2019)
Objective: To assess the levels of a tobacco-specific nitrosamine (NNAL) in non-smokers passively exposed to the second-hand aerosol (SHA) emitted from users of electronic cigarettes (e-cigarettes). ...