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Defective in mitotic arrest 1 (Dma1) ubiquitin ligase controls G1 cyclin degradation
(American Society for Biochemistry and Molecular Biology, 2013-02)
Progression through the G1 phase of the cell cycle is controlled by diverse cyclin-dependent kinases (CDKs) that might be associated to numerous cyclin isoforms. Given such complexity, regulation of ...
Changes in invasive pneumococcal disease caused by streptococcus pneumoniae serotype 1 following introduction of PCV10 and PCV13: findings from the PSERENADE project
(MDPI, 2021)
Streptococcus pneumoniae serotype 1 (ST1) was an important cause of invasive pneumococcal disease (IPD) globally before the introduction of pneumococcal conjugate vaccines (PCVs) containing ST1 antigen. ...
Feeding the brain: effect of nutrients on cognition, synaptic function, and AMPA receptors
(MDPI, 2022)
In recent decades, traditional eating habits have been replaced by a more globalized diet, rich in saturated fatty acids and simple sugars. Extensive evidence shows that these dietary factors contribute ...
Long-term anatomical and functional survival of Boston type 1 keratoprosthesis in congenital aniridia
(Frontiers Media, 2021)
Purpose: To analyze the long-term anatomical survival, functional survival, and complications of Boston type 1 keratoprosthesis (KPro) in the eyes with congenital aniridia-associated keratopathy (AAK). ...
The quantitative changes in the yeast Hsp70 and Hsp90 interactomes upon DNA damage
(Elsevier, 2015-03)
The molecular chaperones Hsp70 and Hsp90 participate in many important cellular processes, including how cells respond to DNA damage. Here we show the results of applied quantitative affinity-purification ...
Skin cancer classification via convolutional neural networks: systematic review of studies involving human experts
(Elsevier, 2021-10)
Background: Multiple studies have compared the performance of artificial intelligence (AI)–based models for automated skin cancer classification to human experts, thus setting the cornerstone for a ...
Pneumococcal nasopharyngeal carriageamong Bhutanese children hospitalizedwith clinical pneumonia: serotypes andviral co-infection
(Springer Nature, 2020-12)
Background: Pneumococcal nasopharyngeal colonization (PNC) generally precedes pneumococcal disease. The purpose of this study was to determine the prevalence of PNC and to identify the pneumococcal ...
Phakomatosis pigmentovascularis cesioflammea
(ACT Publishing, 2019)
nCPAP-induced nose skin injury is a common issue in NICUs all over the world. Damage may vary from simple hyperemia in the region of application of nasal cannulae up to complete destruction of the ...
Adaptación y estudio de propiedades métricas de un cuestionario de valoración del sueño para lactantes y preescolares
(Elsevier, 2018-10)
Introducción: Aunque las alteraciones del sueño en lactantes y preescolares son comunes, no se dispone de un instrumento en español adecuadamente validado para su estudio. El Brief Infant Sleep Questionnaire ...
Lung ultrasound and procalcitonin, improving antibiotic management and avoiding radiation exposure in pediatric critical patients with bacterial pneumonia: a randomized clinical trial
(Springer Nature, 2024)
Background: Pneumonia is a major public health problem with an impact on morbidity and mortality. Its management still represents a challenge. The aim was to determine whether a new diagnostic algorithm ...