Long-term anatomical and functional survival of Boston type 1 keratoprosthesis in congenital aniridia
Author
Dyer, Ariann
De Faria, Alix
Julio, Gemma
de Toledo, Juan Álvarez
Barraquer, Rafael I.
Fideliz de la Paz, Maria
Publication date
2021ISSN
2296-858X
Abstract
Purpose: To analyze the long-term anatomical survival, functional survival, and complications of Boston type 1 keratoprosthesis (KPro) in the eyes with congenital aniridia-associated keratopathy (AAK). Methods: A retrospective review of 12 eyes with congenital aniridia that underwent a Boston type 1 KPro surgery was conducted. A Kaplan–Meier analysis was performed. Anatomical and functional success criteria were KPro retention and a best corrected visual acuity (BCVA) ≤1.3 LogMAR (≥0.05 decimal) at the end of a follow-up period. Postoperative complications were recorded. Results: The mean preoperative BCVA was 2.1 ± 0.9 (range: 3.8–1) LogMAR, and glaucoma was a comorbidity in all the cases. Five years after the surgery, the overall retention rate was 10/12 (83.3%), and 50% had functional success. Only three (25%) of the 12 cases did not achieve a BCVA ≤1.3 LogMAR. The cumulative probability of anatomical success was 92, 79, and 79% after 1, 5, and 10 years, respectively. The cumulative probability of functional success was 57 and 46% after 1 and 5 years, respectively. The mean anatomical and functional survival time was 10 ± 1.3 (95% IC = 7.5–12.3 years) and 3.8 ± 0.9 years (95% IC = 1.8–5.8 years), respectively. The most common postoperative complication was retroprosthetic membrane (RPM) formation in 8/16 cases (66%). The mean number of complications per case was 2.4 ± 1.8 (0–6). Conclusions: The Boston type 1 KPro is a viable option for patients with AAK with good anatomical and functional long-term results. Glaucoma is an important preoperative condition that affects functional results. Retroprosthetic membrane formation seems to have a higher incidence in this condition.
Document Type
Article
Document version
Published version
Language
English
Subject (CDU)
61 - Medical sciences
Keywords
Anirídia
Queratopròtesi de Boston tipus 1
Extrusió
Membrana retroprotèsica
Anirídia associada
Queratopatia
Aniridia
Queratoprótesis Boston tipo 1
Extrusión
Membrana retroprotésica
Aniridia asociada queratopatía
Pages
6
Publisher
Frontiers Media
Collection
8
Is part of
Frontiers in Medicine
Citation
Dyer, Ariann; De Faria, Alix; Julio, Gemma [et al.]. Long-term anatomical and functional survival of Boston Type 1 keratoprosthesis in congenital aniridia. Frontiers in Medicine, 2021, 8, 749063. Disponible en: <https://www.frontiersin.org/articles/10.3389/fmed.2021.749063/full>. Fecha de acceso: 5 feb. 2024. DOI: 10.3389/fmed.2021.749063
This item appears in the following Collection(s)
- Ciències de la Salut [740]
Rights
© 2021 Dyer, De Faria, Julio, Álvarez de Toledo, Barraquer and de la Paz. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by/4.0/