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A dual molecular biointerface combining RGD and KRSR sequences Improves osteoblastic functions by synergizing integrin and cell-membrane proteoglycan binding
(MDPI, 2019-03-21)
Synergizing integrin and cell-membrane heparan sulfate proteoglycan signaling on biomaterials through peptidic sequences is known to have beneficial effects in the attachment and behavior of osteoblasts; ...
All-in-one trifunctional strategy: a cell adhesive, bacteriostatic and bactericidal coating for titanium implants
(Elsevier, 2018-09)
Strategies to inhibit initial bacterial adhesion are extremely important to prevent infection on biomaterial surfaces. However, the simultaneous attraction of desired eukaryotic cells remains a challenge ...
Silver deposition on titanium surface by electrochemical anodizing process reduces bacterial adhesion of Streptococcus sanguinis and Lactobacillus salivarius
(Wiley, 2014-05-30)
Objectives: The aim of this study was to determine the antibacterial properties of silver‐doped titanium surfaces prepared with a novel electrochemical anodizing process. Material and methods: Titanium ...
Determination of fluid leakages in the different screw-retained implant-abutment connections in a mechanical artificial mouth
(Springer, 2015-07-15)
This study shows the potential risk of microfiltration between two different types of implant-abutment connections screwed at 45 Ncm: external and internal. For the first time the use of a mechanical ...
Surface guidance of stem cell behavior: chemically tailored co-presentation of integrin-binding peptides stimulates osteogenic differentiation in vitro and bone formation in vivo
(Elsevier, 2016-10-01)
Surface modification stands out as a versatile technique to create instructive biomaterials that are able to actively direct stem cell fate. Chemical functionalization of titanium has been used in this ...
Mechanical and physicochemical characterization along with biological interactions of a new Ti25Nb21Hf alloy for bone tissue engineering
(SAGE Publications, 2015-03-23)
Nowadays, one of the main challenges in metal implants for bone substitution is the achievement of an elastic modulus close to that of human cortical bone as well as to provide an adequate interaction ...
Surface immobilization and bioactivity of TGF-ß1 inhibitor peptides for bone implant applications
(Wiley, 2016-02-01)
TGF-ß1 is the most related cytokine with the production of fibrotic tissue. It plays an important role on the production of collagen by fibroblasts and other types of cells. The inhibition of this ...
Mineralization of titanium surfaces: biomimetic implants
(MDPI, 2021)
The surface modification by the formation of apatitic compounds, such as hydroxyapatite, improves biological fixation implants at an early stage after implantation. The structure, which is identical to ...
Biofunctionalization strategies on tantalum-based materials for osseointegrative applications
(Springer Nature, 2015)
The use of tantalum as biomaterial for orthopedic applications is gaining considerable attention in the clinical practice because it presents an excellent chemical stability, body fluid resistance, ...
Installing multifunctionality on titanium with RGD-decorated polyurethane-polyurea roxithromycin loaded nanoparticles: toward new osseointegrative therapies
(Wiley, 2015)
A novel class of polyurethane-polyurea nanoparticles (PUUa NPs) to install multifunctionality on biomaterials is presented. Biofunctionalization of titanium with roxithromycin loaded RGD-decorated PUUa ...