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Thermal and non-thermal effects of capacitive–resistive electric transfer application on different structures of the knee: a cadaveric study
(Springer Nature, 2020)
Capacitive–resistive electric transfer therapy is used in physical rehabilitation and sports medicine to treat muscle, bone, ligament and tendon injuries. The purpose is to analyze the temperature change ...
The actin binding protein profilin 2 is a novel regulator of iron homeostasis
(ASH Publication, 2017)
Cellular iron homeostasis is controlled by the iron regulatory proteins (IRPs) 1 and 2 that bind cis-regulatory iron-responsive elements (IRE) on target messenger RNAs (mRNA). We identified profilin 2 ...
Optimized metrics for orthogonal combinatorial CRISPR screens
(Springer Nature, 2023)
CRISPR-based gene perturbation enables unbiased investigations of single and combinatorial genotype-to-phenotype associations. In light of efforts to map combinatorial gene dependencies at scale, choosing ...
The HFE gene is associated to an earlier age of onset and to the presence of diabetic nephropathy in diabetes mellitus type 2
(Springer Nature, 2004)
We initiated the present work to determine whether the presence of the HFE C282Y or H63D mutations could be related to the clinical expression of diabetes mellitus type 2. Two hundred and twenty five ...
Implantation of CPT1AM-expressing adipocytes reduces obesity and glucose intolerance in mice
(Elsevier, 2023-05)
Obesity and its associated metabolic comorbidities are a rising global health and social issue, with novel therapeutic approaches urgently needed. Adipose tissue plays a key role in the regulation of ...
Early management of severe biliary infection in the era of the Tokyo guidelines
(MDPI, 2023)
Sepsis of biliary origin is increasing worldwide and has become one of the leading causes of emergency department admissions. The presence of multi-resistant bacteria (MRB) is increasing, and mortality ...
Analysis of the results and adverse factors of arthroscopic repair of degenerative subscapular lesions
(Elsevier, 2022)
Objective: To carry out a review of degenerative subscapularis ruptures (SSC) after their arthroscopic repair and to evaluate whether the results are comparable in terms of pain and function to those ...
Immobilization of BMP-2 and VEGF within multilayered polydopamine-coated scaffolds and the resulting osteogenic and angiogenic synergy of co-cultured human mesenchymal stem cells and human endothelial progenitor cells
(MDPI, 2020)
We have previously reported the fabrication of a polycaprolactone and hydroxyapatite composite scaffold incorporating growth factors to be used for bone regeneration. Two growth factors were incorporated ...
CDK6 is activated by the atypical cyclin I to promote E2F-mediated gene expression and cancer cell proliferation
(Wiley, 2023)
Cyclin-dependent kinases (CDKs), together with their cyclin partners, are the master cell cycle regulators. Remarkably, the cyclin family was extended to include atypical cyclins, characterized by ...
Análisis de los resultados y los factores adversos de la reparación artroscópica de las lesiones del subescapular de origen degenerativo
(Elsevier, 2021)
Objetivo: Realizar una revisión de roturas del subescapular (SBE) de origen degenerativo tras su reparación por artroscopia y evaluar si los resultados son equiparables en términos de dolor y función a ...