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Now showing items 101-110 of 210
Role of the NUDT enzymes in breast cancer
(MDPI, 2021)
Despite global research efforts, breast cancer remains the leading cause of cancer death in women worldwide. The majority of these deaths are due to metastasis occurring years after the initial treatment ...
Impact of the 13-valent conjugated pneumococcal vaccine on the direct costs of invasive pneumococcal disease requiring hospital admission in children aged < 5 years: a prospective study
(MDPI, 2020)
The lack of invasive pneumococcal disease (IPD) cost studies may underestimate the eect of pneumococcal polysaccharide conjugated vaccines (PCV). The objective of this study was to estimate the direct ...
High-dose methylprednisolone pulses for 3 days vs. low-dose dexamethasone for 10 days in severe, non-critical COVID-19: a retrospective propensity score matched analysis
(MDPI, 2021)
Corticosteroids are largely recommended in patients with severe COVID-19. However, evidence to support high-dose methylprednisolone (MP) pulses is not as robust as that demonstrated for low-dose ...
Pneumonia in children admitted to the national referral hospital in Bhutan: a prospective cohort study
(Elsevier, 2020-06)
Objectives: The study aim was to describe the etiological profile and clinical characteristics of pneumonia among children hospitalized in Thimphu, Bhutan. Methods: This prospective study enrolled ...
Computational modeling as a tool to investigate PPI: from drug design to tissue engineering
(Frontiers Media S.A., 2021)
Protein-protein interactions (PPIs) mediate a large number of important regulatory pathways. Their modulation represents an important strategy for discovering novel therapeutic agents. However, the ...
Development of ARCADIA: a tool for assessing the quality of peer-review reports in biomedical research
(BMJ Publishing Group, 2020)
Objective: To develop a tool to assess the quality of peer-review reports in biomedical research. Methods We conducted an online survey intended for biomedical editors and authors. The survey aimed to ...
Signalling network of breast cancer cells in response to progesterone
(Cold Spring Harbor Laboratory, 2020)
Breast cancer cells enter into the cell cycle following progestin exposure by the activation of signalling cascades involving a plethora of enzymes, transcription factors and co-factors that transmit ...
Victimization as a result of non-consensual dissemination of sexting and psychopathology correlates: an exploratory analysis
(MDPI, 2021)
Sexting is generally known as creating, sending and/or forwarding of sexual content using electronic devices. When such content is non-consensually disseminated, it becomes a criminally relevant behavior. ...
Enquiring beneath the surface: can a gene expression assay shed light into the heterogeneity among newborns with neonatal encephalopathy?
(Springer Nature, 2020)
Background: We aimed to assess whether a gene expression assay provided insights for understanding the heterogeneity among newborns affected by neonatal encephalopathy (NE). Methods: Analysis by RT-qPCR ...
Oral antibiotic prophylaxis lowers surgical site infection in elective colorectal surgery: results of a pragmatic cohort study in Catalonia
(MDPI, 2021)
Background: The role of oral antibiotic prophylaxis (OAP) and mechanical bowel preparation (MBP) in the prevention of surgical site infection (SSI) after colorectal surgery is still controversial. The ...