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Real-world epidemiology of potassium derangements among chronic cardiovascular, metabolic and renal conditions: a population-based analysis
(Dovepress, 2020-09-11)
Background: The aims of the present analysis are to estimate the prevalence of five key chronic cardiovascular, metabolic and renal conditions at the population level, the prevalence of renin–angioten ...
Association between kidney function, nutritional status and anthropometric measures in older people: the screening for CKD among older people across Europe (SCOPE) study
(Springer Nature, 2020-10-02)
Background: Different mechanisms connect the nutritional status with the occurrence and the course of chronic kidney disease (CKD). The end-stage renal disease is complicated by catabolic inflammatory ...
Proactive and systematic multidimensional needs assessment in patients with advanced cancer approaching palliative care: a study protocol
(BMJ Publishing Group, 2020)
Introduction The benefits of palliative care rely on how healthcare professionals assess patients’ needs in the initial encounter/s; crucial to the design of a personalised therapeutic plan. However, ...
Editorial: current challenges for targeting brown fat thermogenesis to combat obesity
(Frontiers Media, 2020-10-27)
Just over a decade has passed since metabolically active brown adipose tissue (BAT) was unequivocally identified in healthy adult humans. Since then, researchers have provided evidence of expression of ...
Direct extrusion of individually encapsulated endothelial and smooth muscle cells mimicking blood vessel structures and vascular native cell alignment
(IOP Science, 2020)
Cardiovascular diseases (CVDs) are considered the principal cause of worldwide death, being atherosclerosis the main etiology. Up to now, the predominant treatment for CVDs has been bypass surgery from ...
Incidence and risk factors for trocar-site incisional hernia detected by clinical and ultrasound examination: a prospective observational study
(Springer Nature, 2020)
Background: Trocar site incisional hernia (TSIH) is the most frequent complication associated with laparoscopic surgery. Few studies currently describe its incidence or risk factors. The aim of this ...
Early short-term postoperative mechanical failures of current ceramic-on-ceramic bearing total hip arthroplasties
(MDPI, 2020)
Although ceramic-on-ceramic (CoC) bearings have been shown to produce the smallest amount of wear volume in vitro as well as in vivo studies when used for total hip arthroplasties (THA), concerns about ...
Daptomycin plus fosfomycin versus daptomycin alone for methicillin-resistant staphylococcus aureus bacteremia and endocarditis: a randomized clinical trial
(Oxford University Press, 2020)
Background: We aimed to determine whether daptomycin plus fosfomycin provides higher treatment success than daptomycin alone for methicillin-resistant Staphylococcus aureus (MRSA) bacteremia and ...
Sensing of nutrients by CPT1C controls SAC1 activity to regulate AMPA receptor trafficking
(Rockefeller University Press, 2020-09)
Carnitine palmitoyltransferase 1C (CPT1C) is a sensor of malonyl-CoA and is located in the ER of neurons. AMPA receptors (AMPARs) mediate fast excitatory neurotransmission in the brain and play a key ...
Predicting clinical outcome with phenotypic clusters in COVID-19 pneumonia: an analysis of 12,066 hospitalized patients from the spanish registry SEMI-COVID-19
(MDPI, 2020)
(1) Background: Different clinical presentations in COVID-19 are described to date, from mild to severe cases. This study aims to identify different clinical phenotypes in COVID-19 pneumonia using cluster ...