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Methylprednisolone pulses plus tacrolimus in addition to standard of care vs. standard of care alone in patients with severe COVID-19. A randomized controlled trial
(Frontiers Media, 2021)
Introduction: Severe lung injury is triggered by both the SARS-CoV-2 infection and the subsequent host-immune response in some COVID-19 patients. Methods: We conducted a randomized, single-center, ...
Sensing of nutrients by CPT1C controls SAC1 activity to regulate AMPA receptor trafficking
(Rockefeller University Press, 2020-09)
Carnitine palmitoyltransferase 1C (CPT1C) is a sensor of malonyl-CoA and is located in the ER of neurons. AMPA receptors (AMPARs) mediate fast excitatory neurotransmission in the brain and play a key ...
Self-learning methodology in simulated environments (MAES©) as a learning tool in perioperative nursing. An evidence-based practice model for acquiring clinical safety competencies
(MDPI, 2021)
Background: The self-learning Methodology in Simulated Environments (Spanish acronym: MAES©, (Murcia, Spain) is a type of self-directed and collaborative training in health sciences. The objective of ...
Predicting clinical outcome with phenotypic clusters in COVID-19 pneumonia: an analysis of 12,066 hospitalized patients from the spanish registry SEMI-COVID-19
(MDPI, 2020)
(1) Background: Different clinical presentations in COVID-19 are described to date, from mild to severe cases. This study aims to identify different clinical phenotypes in COVID-19 pneumonia using cluster ...
New insights of SF1 neurons in hypothalamic regulation of obesity and diabetes
(MDPI, 2021)
Despite the substantial role played by the hypothalamus in the regulation of energy balance and glucose homeostasis, the exact mechanisms and neuronal circuits underlying this regulation remain poorly ...
¿Aprender Medicina a distancia?: percepción de estudiantes confinados por la pandemia COVID-19
(SciELO, 2020-10)
Background: The suspension of face-to-face teaching activity due to the COVID-19 pandemic forced an abrupt transition to distance learning in Spanish universities. Aim: To know how medical students value ...
Effects of the manual therapy approach of segments C0-1 and C2-3 in the flexion-rotation test in patients with chronic neck pain: a randomized controlled trial
(MDPI, 2021-01)
Background: Flexion-rotation test predominantly measures rotation in C1-2 segment. Restriction in flexion-rotation may be due to direct limitation in C1-2, but also to a premature tightening of the alar ...
Differential nasopharyngeal microbiota composition in children according to respiratory health status
(Microbiology Society, 2021)
Acute respiratory infections (ARIs) constitute one of the leading causes of antibiotic administration, hospitalization and death among children <5 years old. The upper respiratory tract microbiota has ...
Challenges for hospital management in supporting nurses to deliver humanized care
(Wiley, 2021)
Hospitals are paying increasing attention to the delivery of humanized care. The purpose of this study was to explore from the nursing perspective what hospital managers might do to facilitate this. A ...
Biceps femoris activation during hamstring strength exercises: a systematic review
(MDPI, 2021)
Background: The aim of the study was to systematically evaluate the biceps femoris long head activation across cross-sectional hamstring strength exercise studies. Methods: A systematic review design ...