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90 years of progesterone: molecular mechanisms of progesterone receptor action on the breast cancer genome
(Bioscientifica Ltd., 2020)
Gene regulation by steroid hormones has been at the forefront in elucidating the intricacies of transcriptional regulation in eukaryotes ever since the discovery by Karlson and Clever that the insect ...
Validity and reliability of the satel 40 Hz stabilometric force platform for measuring quiet stance and dynamic standing balance in healthy subjects
(MDPI, 2020)
Background: A force platform must have validity and reliability for optimal use. The objective of this study was to analyze the validity and the reliability of the Satel 40 Hz stabilometric force platform. ...
Hypothalamic endocannabinoids in obesity: an old story with new challenges
(Springer, 2021)
The crucial role of the hypothalamus in the pathogenesis of obesity is widely recognized, while the precise molecular and cellular mechanisms involved are the focus of intense research. A disrupted ...
Liver CPT1A gene therapy reduces diet‐induced hepatic steatosis in mice and highlights potential lipid biomarkers for human NAFLD
(John Wiley & Sons, Inc., 2020)
The prevalence of nonalcoholic fatty liver disease (NAFLD) has increased drastically due to the global obesity pandemic but at present there are no approved therapies. Here, we aimed to revert high‐fat ...
Does upper cervical manual therapy provide additional benefit in disability and mobility over a physiotherapy primary care program for chronic cervicalgia? A randomized controlled trial
(MDPI, 2020-11-11)
Introduction: Neck pain is a condition with a high incidence in primary care. Patients with chronic neck pain often experience reduction in neck mobility. However, no study to date has investigated the ...
COVID-19: making the best out of a forced transition to online medical teaching. A mixed methods study
(Springer, 2021)
Introduction the COVID-19 pandemic resulted in a decreed confinement in our country from March until the end of term in June 2020. This forced a transition exclusively to distance learning. The aim of ...
Susceptibility to severe acute respiratory syndrome coronavirus 2 infection among children and adults: a seroprevalence study of family households in the Barcelona metropolitan region, Spain
(Oxford University Press, 2021-06)
Background: Susceptibility of children and adults to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and persistence of antibody response to the virus after infection resolution ...
Proactive and systematic multidimensional needs assessment in patients with advanced cancer approaching palliative care: a study protocol
(BMJ Publishing Group, 2020)
Introduction The benefits of palliative care rely on how healthcare professionals assess patients’ needs in the initial encounter/s; crucial to the design of a personalised therapeutic plan. However, ...
Effects of using the surgical mask and FFP2 during the 6-min walking test. A randomized controlled trial
(MDPI, 2021)
During the COVID-19 pandemic, the use of masks has been recommended as a containment measure. The mask is a hindrance to normal breathing that causes discomfort. This could put more work on the respiratory ...
Hypothalamic regulation of obesity
(MDPI, 2021)
Obesity has now reached pandemic proportions and represents a major socioeconomic and health problem in our societies. Up to now, obesity has been considered a medical issue only in high-income countries, ...