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Sensing of nutrients by CPT1C regulates late endosome/lysosome anterograde transport and axon growth
(eLife Sciences Publications, 2019)
Anterograde transport of late endosomes or lysosomes (LE/Lys) is crucial for proper axon growth. However, the role of energetic nutrients has been poorly explored. Malonyl-CoA is a precursor of fatty ...
Real-world epidemiology of potassium derangements among chronic cardiovascular, metabolic and renal conditions: a population-based analysis
(Dovepress, 2020)
Background: The aims of the present analysis are to estimate the prevalence of five key chronic cardiovascular, metabolic and renal conditions at the population level, the prevalence of renin–angioten ...
Hormone-control regions mediate steroid receptor–dependent genome organization
(Cold Spring Harbor Laboratory Press, 2019)
In breast cancer cells, some topologically associating domains (TADs) behave as hormonal gene regulation units, within which gene transcription is coordinately regulated in response to steroid hormones. ...
Gender commonalities and differences in risk and protective factors of suicidal thoughts and behaviors: a cross-sectional study of Spanish university students
(Wiley, 2019-11)
AIM: To assess gender differences in the association between risk/protective factors and suicidal thoughts and behaviors (STB); and whether there is any gender-interaction with those factors and STB; ...
“EspaiJove.net”- a school-based intervention programme to promote mental health and eradicate stigma in the adolescent population: study protocol for a cluster randomised controlled trial
(Springer Nature, 2018)
Background: One half of adults who develop any mental disorder do so during adolescence. Previous literature showed that Mental Health Literacy (MHL) interventions impact mental health knowledge, reduce ...
Knowledge management for systems biology a general and visually driven framework applied to translational medicine
(BMC Systems Biology, 2011)
Background: To enhance our understanding of complex biological systems like diseases we need to put all of the available data into context and use this to detect relations, pattern and rules which allow ...
Conocimiento y uso de mecanismos de coordinación clínica de servicios de salud de Latinoamérica
(Elsevier, 2018)
Objetivo: Analizar el nivel de conocimiento y uso, y las características del uso, de los mecanismos de coordinación clínica entre niveles de atención en redes de servicios de salud de seis países de ...
Understanding patients’ experiences of the wish to hasten death: an updated and expanded systematic review and meta-ethnography
(BMJ Publishing Group, 2017)
Objectives: Patients with advanced disease sometimes express a wish to hasten death (WTHD). In 2012, we published a systematic review and meta-ethnography of qualitative studies examining the experience ...
Psychometric properties of the spanish version of the Jefferson Scale of Empathy: making sense of the total score through a second order confirmatory factor analysis
(Springer Nature, 2016-09-19)
Background: Empathy is a key aspect of the physician-patient interactions. The Jefferson Scale of Empathy (JSE) is one of the most used empathy measures of medical students. The development of cross-cultural ...
Complete loss of EPCAM immunoexpression identifies EPCAM deletion carriers in MSH2-negative colorectal neoplasia
(MDPI, 2020)
The use of epithelial cell adhesion molecule (EPCAM) immunohistochemistry (IHC) is not included in the colorectal cancer (CRC) screening algorithm to detect Lynch syndrome (LS) patients. The aim of the ...