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Now showing items 181-190 of 375
Subtle skin changes that suggest severe disease
(BMA. British Medical Association, 2018-05-18)
Dysregulation of the immune system in HIV/HCV-coinfected patients according to liver stiffness status
(MDPI, 2018)
Background: Advanced cirrhosis is related to alterations in immunity. We aimed to evaluate the levels of peripheral CD4+ T cells (Tregs) and plasma cytokine in patients coinfected with human immunodeficiency ...
Effects of sedatives and opioids on trigger and cycling asynchronies throughout mechanical ventilation: an observational study in a large dataset from critically ill patients
(Springer Nature, 2019-07-05)
Background: In critically ill patients, poor patient-ventilator interaction may worsen outcomes. Although sedatives are often administered to improve comfort and facilitate ventilation, they can be ...
The european hematology association roadmap for european hematology research: a consensus document
(Ferrata Storti Foundation, 2016)
The European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical ...
Signalling network of breast cancer cells in response to progesterone
(Cold Spring Harbor Laboratory, 2020)
Breast cancer cells enter into the cell cycle following progestin exposure by the activation of signalling cascades involving a plethora of enzymes, transcription factors and co-factors that transmit ...
Enquiring beneath the surface: can a gene expression assay shed light into the heterogeneity among newborns with neonatal encephalopathy?
(Springer Nature, 2020)
Background: We aimed to assess whether a gene expression assay provided insights for understanding the heterogeneity among newborns affected by neonatal encephalopathy (NE). Methods: Analysis by RT-qPCR ...
The critical size is set at a single-cell level by growth rate to attain homeostasis and adaptation
(Nature Research, 2012-08-21)
Budding yeast cells are assumed to trigger Start and enter the cell cycle only after they attain a critical size set by external conditions. However, arguing against deterministic models of cell size ...
RE-irradiation of silver nanoparticles obtained by laser ablation in water and assessment of their antibacterial effect
(Elsevier, 2018-12-20)
The rapid evolution of resistant bacteria is a huge problem in medicine because makes the treatment of infections more and more difficult. The bactericidal properties of noble metal nanoparticles could ...
Multimorbidity patterns in low-middle and high income regions: a multiregion latent class analysis using ATHLOS harmonised cohorts
(BMJ Publishing Group, 2020)
Our aim was to determine clusters of non-communicable diseases (NCDs) in a very large, population-based sample of middle-aged and older adults from low- and middle-income (LMICs) and high-income (HICs) ...
Hymenal tags of the newborn
(ACT Publishing Group Limited, 2019)
Evaluation of female newborn genitalia should always be carried out at pre-discharge visit in hospital nurseries in order to exclude gross malformations, potentially compatible with genetic and/or ...