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Now showing items 181-190 of 375
A systematic analysis of orphan cyclins reveals CNTD2 as a new oncogenic driver in lung cancer
(Scientific Reports, 2017-08-31)
As lung cancer has increased to the most common cause of cancer death worldwide, prognostic
biomarkers and efective targeted treatments remain lacking despite advances based on patients’
stratifcation. ...
High flow conditioned oxygen therapy for prevention of reintubation in critically ill patients: a preliminary cohort study
(ClinMed International Library, 2015-12-31)
Objective: To determine the impact of delivering high flow conditioned oxygen therapy (HFO) through nasal cannula on prevention of reintubation in mechanically ventilated (MV) critically ill patients. ...
Genomic and serologic characterization ofenterovirus A71 brainstem encephalitis
(Wolters Kluwer, 2020)
Objective: In 2016, Catalonia experienced a pediatric brainstem encephalitis outbreak caused by enterovirus A71 (EV-A71). Conventional testing identified EV in the periphery but rarely in CSF. Metagenomic ...
Immobilization of BMP-2 and VEGF within multilayered polydopamine-coated scaffolds and the resulting osteogenic and angiogenic synergy of co-cultured human mesenchymal stem cells and human endothelial progenitor cells
(MDPI, 2020)
We have previously reported the fabrication of a polycaprolactone and hydroxyapatite composite scaffold incorporating growth factors to be used for bone regeneration. Two growth factors were incorporated ...
Survival benefit of multidisciplinary care in amyotrophic lateral sclerosis in Spain: association with noninvasive mechanical ventilation
(Dove Press, 2019)
Purpose: Multidisciplinary care has become the preferred model of care for patients with amyotrophic lateral sclerosis (ALS). It is assumed that the sum of interventions associated with this approach ...
Chronic kidney disease in the context of multimorbidity patterns: the role of physical performance: the screening for CKD among older people across Europe (SCOPE) study
(Springer Nature, 2020-10-02)
Background: Chronic kidney disease (CKD) is known to be associated with several co-occurring conditions. We aimed at exploring multimorbidity patterns associated with CKD, as well as the impact of ...
Nurr1 protein Is required for N-methyl-d-aspartic acid (NMDA) receptor-mediated neuronal survival
(Elsevier, 2012-03-30)
NMDA receptor (NMDAR) stimulation promotes neuronal survival during brain development. Cerebellar granule cells (CGCs) need NMDAR stimulation to survive and develop. These neurons differentiate and ...
“EspaiJove.net”- a school-based intervention programme to promote mental health and eradicate stigma in the adolescent population: study protocol for a cluster randomised controlled trial
(Springer Nature, 2018)
Background: One half of adults who develop any mental disorder do so during adolescence. Previous literature showed that Mental Health Literacy (MHL) interventions impact mental health knowledge, reduce ...
CPT1C promotes human mesenchymal stem cells survival under glucose deprivation through the modulation of autophagy
(Nature Research, 2018-05-03)
Human mesenchymal stem cells (hMSCs) are widely used in regenerative medicine. In some
applications, they must survive under low nutrient conditions engendered by avascularity. Strategies to
improve ...
Burden of disease attributable to second-hand smoke exposure: a systematic review
(Elsevier, 2019-12)
Our aim was to provide a systematic review of studies on the burden of disease due to second-hand smoke (SHS) exposure, reviewing methods, exposure assessment, diseases causally linked to SHS, health ...