Now showing items 1-3 of 3

    • CDK6 is activated by the atypical cyclin I to promote E2F-mediated gene expression and cancer cell proliferation 

      Quandt, Eva; Masip, Núria; Hernández-Ortega, Sara; Sánchez-Botet, Abril; Gasa, Laura; Fernández-Elorduy, Ainhoa; Plutta, Sara; Martínez-Láinez, Joan Marc; Bru, Samuel; Munoz-Torres, Pau M.; Floor, Martin; Villà-Freixa, Jordi; Morris, May C.; Vidal, August; Villanueva, Alberto; Clotet, Josep; Ribeiro, Mariana P. C. (Molecular Oncology, 2023)
      Cyclin-dependent kinases (CDKs), together with their cyclin partners, are the master cell cycle regulators. Remarkably, the cyclin family was extended to include atypical cyclins, characterized by ...
    • CDK6 is activated by the atypical cyclin I to promote E2F-mediated gene expression and cancer cell proliferation 

      Quandt Herrera, Eva; Masip Sales, Núria; Hernández Ortega, Sara; Sánchez‑Botet, Abril; Gasa, Laura; Fernández-Elorduy, Ainhoa; Plutta, Sara; Martínez Láinez, Joan Marc; Bru Rullo, Samuel; Munoz-Torres, Pau M.; Floor, Martin; Villà-Freixa, Jordi; Morris, May C.; Vidal, August; Villanueva, Alberto; Clotet, Josep; Ribeiro, Mariana (Molecular Oncology, 2023)
      Cyclin-dependent kinases (CDKs), together with their cyclin partners, are the master cell cycle regulators. Remarkably, the cyclin family was extended to include atypical cyclins, characterized by ...
    • The atypical cyclin CNTD2 promotes colon cancer cell proliferation and migration 

      Sánchez Botet, Abril; Gasa Colom, Laura; Quandt Herrera, Eva; Hernández Ortega, Sara; Jiménez Jiménez, Javier; Mezquita Mas, Pau; Carrasco García, Miguel Ángel; Kron, Stephen J.; Vidal, August; Villanueva, Alberto; P.C. Ribeiro, Mariana; Clotet Erra, Josep (2018-08-07)
      Colorectal cancer (CRC) is one of the most common cancers worldwide, with 8–10% of these tumours presenting a BRAF (V600E) mutation. Cyclins are known oncogenes deregulated in many cancers, but the role ...