Show simple item record

dc.contributor.authorGuillem Martí, Jordi
dc.contributor.authorCinca, Núria
dc.contributor.authorPunset Fuste, Miquel
dc.contributor.authorGarcía Cano, Irene
dc.contributor.authorGil Mur, Francisco Javier
dc.contributor.authorGuilemany, José Maria
dc.contributor.authorDosta, Sergi
dc.identifier.citationGuillem-Martí, Jordi; Cinca, Núria; Punset, Miquel; García Cano, Irene; Gil Mur, Francesc Xavier; Guilemany, José Maria; Dosta, Sergi. «Porous titanium-hydroxyapatite composite coating obtained on titanium by cold gas spray with high bond strength for biomedical applications». Colloids and Surfaces B: Biointerfaces, 2019, vol. 180, p. 245-253.
dc.description.abstractThe lack of bioactivity of titanium (Ti) is one of the main drawbacks for its application in biomedical implants since it can considerable reduce its osseointegration capacities. One strategy to overcome this limitation is the coating of Ti with hydroxyapatite (HA), which presents similar chemical composition than bone. Nonetheless, most of the strategies currently used generate a non-stable coating and may produce the formation of amorphous phases when high temperatures are used. Herein, we proposed to generate a Ti-HA composite coating on Ti surface to improve the stability of the bioactive coating. The coating was produced by cold gas spraying, which uses relatively low temperatures, and compared to a Ti coating. The coating was thoroughly characterized in terms of morphology, roughness, porosity and phase composition. In addition, the coating was mechanically characterized using a tensile loading machine. Finally, biological response was evaluated after seeding SaOS-2 osteoblasts and measuring cell adhesion, proliferation and differentiation. The novel Ti-HA coating presented high porosity and high adhesion and bond strengths. No change in HA phases was observed after coating formation. Moreover, osteoblast-like cells adhered, proliferated and differentiated on Ti-HA coated surfaces suggesting that the novel coating might be a good candidate for biomedical applications.en
dc.relation.ispartofColloids and Surfaces B: Biointerfacesca
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.subject.otherMaterials biomèdicsca
dc.subject.otherBiomedical materialsca
dc.subject.otherMateriales biomédicosca
dc.subject.otherHydroxyapatite coatingca
dc.titlePorous titanium-hydroxyapatite composite coating obtained on titanium by cold gas spray with high bond strength for biomedical applicationsca

Files in this item


This item appears in the following Collection(s)

Show simple item record
Except where otherwise noted, this item's license is described as