Porous titanium-hydroxyapatite composite coating obtained on titanium by cold gas spray with high bond strength for biomedical applications
Author
Guillem Martí, Jordi
Cinca, Núria
Punset Fuste, Miquel
García Cano, Irene
Gil Mur, Francisco Javier
Guilemany, José Maria
Dosta, Sergi
Publication date
2019-04-24ISSN
0927-7765
Abstract
The lack of bioactivity of titanium (Ti) is one of the main drawbacks for its application in biomedical implants since it can considerable reduce its osseointegration capacities. One strategy to overcome this limitation is the coating of Ti with hydroxyapatite (HA), which presents similar chemical composition than bone. Nonetheless, most of the strategies currently used generate a non-stable coating and may produce the formation of amorphous phases when high temperatures are used. Herein, we proposed to generate a Ti-HA composite coating on Ti surface to improve the stability of the bioactive coating. The coating was produced by cold gas spraying, which uses relatively low temperatures, and compared to a Ti coating. The coating was thoroughly characterized in terms of morphology, roughness, porosity and phase composition. In addition, the coating was mechanically characterized using a tensile loading machine. Finally, biological response was evaluated after seeding SaOS-2 osteoblasts and measuring cell adhesion, proliferation and differentiation. The novel Ti-HA coating presented high porosity and high adhesion and bond strengths. No change in HA phases was observed after coating formation. Moreover, osteoblast-like cells adhered, proliferated and differentiated on Ti-HA coated surfaces suggesting that the novel coating might be a good candidate for biomedical applications.
Document Type
Article
Document version
Accepted version
Language
English
Subject (CDU)
54 - Química
61 - Medicina
Keywords
Titani
Titanio
Titanium
Materials biomèdics
Biomedical materials
Materiales biomédicos
Hydroxyapatite coating
Pages
33
Publisher
Elsevier
Collection
180;
Is part of
Colloids and Surfaces B: Biointerfaces
Citation
Guillem-Martí, Jordi; Cinca, Núria; Punset, Miquel; García Cano, Irene; Gil Mur, Francesc Xavier; Guilemany, José Maria; Dosta, Sergi. «Porous titanium-hydroxyapatite composite coating obtained on titanium by cold gas spray with high bond strength for biomedical applications». Colloids and Surfaces B: Biointerfaces, 2019, vol. 180, p. 245-253. https://doi.org/10.1016/j.colsurfb.2019.04.048
This item appears in the following Collection(s)
- Ciències de la Salut [532]
Rights
http://creativecommons.org/licenses/by-nc-nd/4.0/
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Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by-nc-nd/4.0/