Browsing by Subject "Angiogenesis"
Now showing items 1-7 of 7
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A mini review focused on the proangiogenic role of silicate ions released from silicon-containing biomaterials
(2017-04-06)Angiogenesis is considered an important issue in the development of biomaterials for the successful regeneration of tissues including bone. While growth factors are commonly used with biomaterials to ... -
Assessing the potential role of copper and cobalt in stimulating angiogenesis for tissue regeneration
(PLoS One, 2021)The use of copper (Cu2+) and cobalt (Co2+) has been described to stimulate blood vessel formation, a key process for the success of tissue regeneration. However, understanding how different concentrations ... -
Bioluminescent and micro-computed tomography imaging of bone repair induced by fibrin-binding growth factors
(Acta Biomaterialia, 2014)In this work we have evaluated the capacity of bone morphogenetic protein-2 (BMP-2) and fibrin-binding platelet-derived growth factor-BB (PDGF-BB) to support cell growth and induce bone regeneration ... -
Hyperbaric oxygen treatment of tissue-engineered mucosa enhances secretion of angiogenic factors in vitro
(Tissue Engineering Part A, 2014)The survival of tissue-engineered mucosa (TEM) after implantation is mostly dependent on the presence of blood vessels for continuous oxygen supply. Therefore the stimulation of vascularization of TEM ... -
Immobilization of BMP-2 and VEGF within multilayered polydopamine-coated scaffolds and the resulting osteogenic and angiogenic synergy of co-cultured human mesenchymal stem cells and human endothelial progenitor cells
(International Journal of Molecular Sciences, 2020)We have previously reported the fabrication of a polycaprolactone and hydroxyapatite composite scaffold incorporating growth factors to be used for bone regeneration. Two growth factors were incorporated ... -
Multiple ion scaffold-based delivery platform for potential application in early stages of bone regeneration
(Materials, 2021)Bone has the intrinsic capacity to regenerate itself, as long as the damage is small, through the sequential stimulation of specific phases, such as angiogenesis followed by osteogenesis. However, when ... -
The impact of KRAS mutations on VEGF-A production and tumour vascular network
(BMC Cancer, 2013-03-18)Background: The malignant potential of tumour cells may be influenced by the molecular nature of KRAS mutations being codon 13 mutations less aggressive than codon 12 ones. Their metabolic profile is ...