Effect of a home-base core stability exercises in hereditary ataxia. A randomized controlled trial. A pilot randomized controlled trial
Author
Fernández-Lago, Helena
Peláez-Hervás, Selma
Serra-Rusiñol, Laura
Masbernat-Almenara, Maria
Publication date
2024ISSN
2330-1619
Abstract
Background: Core stability exercises (CSE) have been shown to be effective in improving trunk function in several neurological diseases, but the evidence is scarce on Hereditary Ataxias (HA). Objective: To evaluate the effectiveness of a 5-week home-based CSE program in terms of ataxia severity, trunk function, balance confidence, gait speed, lower limb motor function, quality of life, health status and falls rate in HA individuals at short- and long-term. Methods: This is an assessor-blind randomized controlled clinical trial parallel group 1:1. The individuals were divided in experimental group (EG) performed standard care in addition to CSE, and control group (CG) performed standard care alone. The CSE home-program was conducted 1-h/day, 5-day/week for 5-week. The assessment was performed at baseline, endpoint (5-week), and follow-up (10-week). The primary outcomes were ataxia severity assessed by the Scale for the Assessment and Rating of Ataxia and trunk function assessed by Spanish-version of Trunk Impairment Scale 2.0. The secondary outcomes were balance confidence assessed by Activities-specific Balance Confidence (ABC), gait speed by 4-meter walk test (4-MWT), the lower limb motor function by 30-s sit-to-stand, quality of life by EuroQol 5-dimension 5-level (EQ-5D-5L), health-status by EQ-5D and falls rate. Results: Twenty-three HA individuals were recruited (51.8 ± 11.10 years). Statistically significant group-time interaction was shown in ABC (F:5.539; P = 0.007), EQ-5D-5L Total (F:4.836; P = 0.013), EQ 5D (F:7.207; P = 0.006). Conclusions: No statistical differences between groups for ataxia severity and trunk function were observed. However, were differences for balance confidence, gait speed, quality of life, and falls rate in HA individuals.
Document Type
Article
Document version
Published version
Language
English
Subject (CDU)
61 - Medical sciences
Keywords
Atàxia hereditària
Ataxia hereditaria
Hereditary ataxia
Pages
10
Publisher
John Wiley & Sons
Is part of
Movement Disorders Clinical Practice
Citation
Cabanas-Valdés, Rosa; Fernández-Lago, Helena; Peláez-Hervás, Selma [et al.]. Effect of a home-base core stability exercises in hereditary ataxia. A randomized controlled trial. A pilot randomized controlled trial. Movement Disorders Clinical Practice, 2024, p. 1-10. Disponible en: <https://movementdisorders.onlinelibrary.wiley.com/doi/10.1002/mdc3.14036>. Fecha de acceso: 5 abr. 2024. DOI: 10.1002/mdc3.14036
This item appears in the following Collection(s)
- Ciències de la Salut [725]
Rights
© 2024 The Authors.Movement Disorders Clinical Practicepublished by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society. This is an open access article under the terms of theCreative Commons AttributionLicense, which permits use, distribution and reproduction in anymedium, provided the original work is properly cited.
Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by/4.0/