Localized refractive changes induced by symmetric and progressive asymmetric intracorneal ring segments assessed with a 3D finite-element model
Publication date
2023ISSN
2306-5354
Abstract
To build a representative 3D finite element model (FEM) for intracorneal ring segment (ICRS) implantation and to investigate localized optical changes induced by different ICRS geometries, a hyperelastic shell FEM was developed to compare the effect of symmetric and progressive asymmetric ICRS designs in a generic healthy and asymmetric keratoconic (KC) cornea. The resulting deformed geometry was assessed in terms of average curvature via a biconic fit, sagittal curvature (K), and optical aberrations via Zernike polynomials. The sagittal curvature map showed a locally restricted flattening interior to the ring (Kmax −11 to −25 dpt) and, in the KC cornea, an additional local steepening on the opposite half of the cornea (Kmax up to +1.9 dpt). Considering the optical aberrations present in the model of the KC cornea, the progressive ICRS corrected vertical coma (−3.42 vs. −3.13 µm); horizontal coma (−0.67 vs. 0.36 µm); and defocus (2.90 vs. 2.75 µm), oblique trefoil (−0.54 vs. −0.08 µm), and oblique secondary astigmatism (0.48 vs. −0.09 µm) aberrations stronger than the symmetric ICRS. Customized ICRS designs inspired by the underlying KC phenotype have the potential to achieve more tailored refractive corrections, particularly in asymmetric keratoconus patterns.
Document Type
Article
Document version
Published version
Language
English
Subject (CDU)
617 - Surgery. Orthopaedics. Ophthalmology
Keywords
Pages
12
Publisher
MDPI
Collection
10; 9
Is part of
Bioengineering
Citation
García de Oteyza, Gonzalo; Álvarez de Toledo, Juan; Barraquer, Rafael I. [et al.]. Localized refractive changes induced by symmetric and progressive asymmetric intracorneal ring segments assessed with a 3D finite-element model. Bioengineering, 2023, 10(9), 1014. Disponible en: <https://www.mdpi.com/2306-5354/10/9/1014>. Fecha de acceso: 14 feb. 2024. DOI: 10.3390/bioengineering10091014
Grant agreement number
info:eu-repo/grantAgreement/EC/H2020/956720
Note
This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 956720 and from the Swiss National Science Foundation (Ambizione PZ00P2_174113 to S.K.).
This item appears in the following Collection(s)
- Ciències de la Salut [966]
Rights
© 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by/4.0/


