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dc.contributor.authorGarcía de Oteyza, Gonzalo
dc.contributor.authorÁlvarez de Toledo, Juan
dc.contributor.authorBarraquer, Rafael I.
dc.contributor.authorKling, Sabine
dc.date.accessioned2024-02-14T14:25:01Z
dc.date.available2024-02-14T14:25:01Z
dc.date.issued2021
dc.identifier.citationGarcía de Oteyza, Gonzalo; Álvarez de Toledo, Juan; Barraquer, Rafael I. [et al.]. Refractive changes of a new asymmetric intracorneal ring segment with variable thickness and base width: a 2D finite-element model. PLoS ONE, 2021, 16(9), e0257222. Disponible en: <https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0257222>. Fecha de acceso: 14 feb. 2024. DOI: 10.1371/journal.pone.0257222ca
dc.identifier.issn1932-6203ca
dc.identifier.urihttp://hdl.handle.net/20.500.12328/4089
dc.description.abstractPurpose: To evaluate the local geometric effects of a unilateral intrastromal ring segment with a combined variation of ring thickness and base width in a finite element simulation, and to compare it against the isolated effect of thickness or base width variation alone. Methods: A two-dimensional finite-element model of a transversely isotropic cornea was created assuming either axisymmetric stress or plane strain condition. The model geometry was composed of a three-layered corneal tissue (epithelium, anterior and posterior stroma) fixed at the limbus. The implantation of a triangular-shape asymmetric ring segment with varying ring thickness (150 to 300 μm) and base width (600 to 800 μm) was simulated. Also, changes induced by thickness or base width alone were studied and compared their combined effect in the asymmetric ring segment. Geometrical deformation of the simulated cornea and sagittal curvature were the main parameters of study. Results: Increasing ring thickness and base width along the arc of the asymmetric ring segment produced a more pronounced flattening in this part of the ring. The asymmetric design did find a good balance between maximizing corneal flattening at one end and minimizing it at the other end, compared to the isolated effect of ring thickness and width. Ring thickness was the most robust parameter in flattening both, the central and peripheral cornea. Conclusion: The finite-element model permitted a theoretical study of corneal deformation undergoing implantation of realistic and hypothetical ring geometries. Intracorneal asymmetric ring segments with varying thickness and base width can be a good alternative in corneas with asymmetric keratoconus phenotypes.ca
dc.format.extent14ca
dc.language.isoengca
dc.publisherPublic Library of Scienceca
dc.relation.ispartofPLoS ONEca
dc.relation.ispartofseries16;9
dc.rights© 2021 García de Oteyza et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.ca
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subject.otherOftalmologiaca
dc.subject.otherOftalmologíaca
dc.subject.otherOphthalmologyca
dc.titleRefractive changes of a new asymmetric intracorneal ring segment with variable thickness and base width: a 2D finite-element modelca
dc.typeinfo:eu-repo/semantics/articleca
dc.description.versioninfo:eu-repo/semantics/publishedVersionca
dc.rights.accessLevelinfo:eu-repo/semantics/openAccess
dc.embargo.termscapca
dc.subject.udc617ca
dc.identifier.doihttps://dx.doi.org/10.1371/journal.pone.0257222ca


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© 2021 García de Oteyza et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by/4.0/
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