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dc.contributor.authorArmero, Georgina
dc.contributor.authorPenela Sánchez, Daniel
dc.contributor.authorBelmonte, Jordina
dc.contributor.authorGómez-Barroso, Diana
dc.contributor.authorLarrauri, Amparo
dc.contributor.authorHenares Bonilla , Desirée
dc.contributor.authorVallejo, Violeta
dc.contributor.authorJordan, Iolanda
dc.contributor.authorMuñoz-Almagro, Carmen
dc.contributor.authorBrotons, Pedro
dc.contributor.authorLaunes, Cristian
dc.date.accessioned2022-07-06T17:51:48Z
dc.date.available2022-07-06T17:51:48Z
dc.date.issued2022
dc.identifier.citationArmero, Georgina; Penela Sánchez, Daniel; Belmonte, Jordina [et al.]. Concentrations of nitrogen compounds are related to severe rhinovirus infection in infants. A time-series analysis from the reference area of a pediatric university hospital in Barcelona. Pediatric Pulmonology, 2022, p. 1-9. Disponible en: <https://onlinelibrary.wiley.com/doi/10.1002/ppul.26021>. Fecha de acceso: 6 jul. 2022. DOI: 10.1002/ppul.26021ca
dc.identifier.issn1099-0496ca
dc.identifier.urihttp://hdl.handle.net/20.500.12328/3360
dc.description.abstractBackground: There is scarce information focused on the effect of weather conditions and air pollution on specific acute viral respiratory infections, such as rhinovirus (RV), with a wide clinical spectrum of severity. Objective: The aim of this study was to analyze the association between episodes of severe respiratory tract infection by RV and air pollutant concentrations (NOx and SO2) in the reference area of a pediatric university hospital. Methods: An analysis of temporal series of daily values of NOx and SO2, weather variables, circulating pollen and mold spores, and daily number of admissions in the pediatric intensive care unit (PICU) with severe respiratory RV infection (RVi) in children between 6 months and 18 years was performed. Lagged variables for 0–5 days were considered. The study spanned from 2010 to 2018. Patients with comorbidities were excluded. Results: One hundred and fifty patients were admitted to the PICU. Median age was 19 months old (interquartile range [IQR]: 11–47). No relationship between RV-PICU admissions and temperature, relative humidity, cumulative rainfall, or wind speed was found. Several logistic regression models with one pollutant and two pollutants were constructed but the best model was that which included average daily NOx concentrations. Average daily NOx concentrations were related with the presence of PICU admissions 3 days later (odds ratio per IQR-unit increase: 1.64, 95% confidence interval: 1.20–2.25)). Conclusions: This study has shown a positive correlation between NOx concentrations at Lag 3 and children's PICU admissions with severe RV respiratory infection. Air pollutant data should be taken into consideration when we try to understand the severity of RVis.en
dc.format.extent9ca
dc.language.isoengca
dc.publisherJohn Wiley & Sonsca
dc.relation.ispartofPediatric Pulmonologyca
dc.relation.urihttps://onlinelibrary.wiley.com/doi/10.1002/ppul.26021ca
dc.rights© 2022 The Authors. Pediatric Pulmonology published by Wiley Periodicals LLC. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in anymedium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.en
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.otherContaminació de l'aireca
dc.subject.otherInfeccions respiratòries víriques agudes específiquesca
dc.subject.otherInfeccions respiratòriesca
dc.subject.otherRinovirusca
dc.subject.otherEpisodis d'infecció greuca
dc.subject.otherUnitat de cures intensives pediàtriquesca
dc.subject.otherContaminación del airees
dc.subject.otherInfecciones respiratorias víricas agudas específicases
dc.subject.otherInfecciones respiratoriases
dc.subject.otherRinoviruses
dc.subject.otherEpisodios de infección gravees
dc.subject.otherUnidad de cuidados intensivos pediátricoses
dc.subject.otherAir pollutionen
dc.subject.otherSpecific acute viral respiratory infectionsen
dc.subject.otherRespiratory infectionsen
dc.subject.otherRhinovirusen
dc.subject.otherEpisodes of severe infectionen
dc.subject.otherPediatric Intensive Care Uniten
dc.titleConcentrations of nitrogen compounds are related to severe rhinovirus infection in infants. A time-series analysis from the reference area of a pediatric university hospital in Barcelonaen
dc.typeinfo:eu-repo/semantics/articleca
dc.description.versioninfo:eu-repo/semantics/publishedVersionca
dc.rights.accessLevelinfo:eu-repo/semantics/openAccess
dc.embargo.termscapca
dc.subject.udc61ca
dc.subject.udc616.9ca
dc.identifier.doihttps://dx.doi.org/10.1002/ppul.26021ca


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© 2022 The Authors. Pediatric Pulmonology published by Wiley Periodicals LLC. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in anymedium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by-nc-nd/4.0/