Limited joint mobility progression in type 1 diabetes: a 15-year follow-up study
Author
Labad, Javier
Rozadilla Sacanell, Antoni
Garcia-Sancho, Paula
Nolla, Joan M.
Montanya, Eduard
Publication date
2018ISSN
1687-8337
Abstract
Objective. To assess the evolution of joint mobility over a period of 15 years in type 1 diabetic patients and healthy controls and to determine whether microalbuminuria is associated with a different evolution of joint mobility. Methods. Joint mobility of hand and wrist was determined in 63 patients with type 1 diabetes and 63 healthy subjects. Fifteen years later, 37 (58.7%) diabetic patients and 16 (25.4%) healthy subjects were studied again. Joint mobility was assessed with the Prayer sign and by measuring the angle of maximal flexion of the fifth and third metacarpophalangeal (MCP) joints and wrist. Patients with diabetes were visited 2–4 times every year with regular assessment of glycated hemoglobin (HbA1c), urinary albumin excretion (UAE), and ophthalmoscopy. Results. Fifteen years after the initial exam, diabetic patients showed reduced flexion of the fifth MCP joint (82.6 ± 5.8 versus 76.0 ± 6.4 degrees, ) and wrist (75.9 ± 8.1 versus 73.2 ± 7.4 degrees, ) compared to baseline examination. Joint mobility did not change significantly in healthy subjects. Patients with microalbuminuria showed greater reduction in hand joint mobility than diabetic patients with normal UAE or than healthy subjects (). Conclusions. In type 1 diabetic patients, the severity of LJM progresses with time, and the progression is enhanced in patients with microalbuminuria.
Document Type
Article
Document version
Published version
Language
English
Subject (CDU)
61 - Medical sciences
616.4 - Pathology of the lymphatic system, haemopoietic (haematopoietic) organs, endocrines
Keywords
Diabetis
Microalbuminúria
Mobilitat articular
Diabetes
Microalbuminuria
Movilidad articular
Diabetes
Microalbuminuria
Joint mobility
Pages
6
Publisher
Hindawi Limited
Is part of
International Journal of Endocrinology
Citation
Labad, Javier; Rozadilla Sacanell, Antoni; Garcia-Sancho, Paula [et al.]. Limited joint mobility progression in type 1 diabetes: a 15-year follow-up study. International Journal of Endocrinology, 2018, 1897058. Disponible en: <https://www.hindawi.com/journals/ije/2018/1897058/>. Fecha de acceso: 25 ene. 2022. DOI: 10.1155/2018/1897058
This item appears in the following Collection(s)
- Ciències de la Salut [745]
Rights
© 2018 Javier Labad et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by/4.0/