Current and future perspectives in lung cancer prevention
Publication date
2020ISSN
2617-2216
Abstract
Smoking is one of the leading causes of morbidity and mortality worldwide. Tobacco smoke contains thousands of different heterogeneous substances, dozens of them classified as carcinogenic for humans, including tobacco-specific nitrosamines (TSNAs), metals and polycyclic aromatic hydrocarbons, among others. Deleterious effects of tobacco consumption occur not only in active smokers, but also in people passively exposed to secondhand and thirdhand smoke, the latter including children (1). There are diverse disorders associated with tobacco smoking, including cardiovascular and respiratory conditions, and cancer in multiple sites and organs (e.g., urinary bladder, stomach, lung). Lung cancer is one of the most concerning disorders associated with smoking and the first cause of cancer mortality worldwide. In 2018, an estimated 1.76 million people died of lung cancer, a higher figure than the sum of the second and third top causes of cancer-specific mortality (i.e., colorectal and stomach) (2). Lung cancer shows an overall 5-year survival rate from diagnosis of around 15–20% (3), one of the lowest among all types of cancer, result of a frequent late diagnosis in advanced stages, when the prognosis is poorer, due to the commonly unspecific initial symptoms. This survival rate has remained almost invariable for years.
Document Type
Article
Document version
Published version
Language
English
Subject (CDU)
61 - Medical sciences
616.2 - Pathology of the respiratory system. Complaints of the respiratory organs
Keywords
Tabaquism
Morbiditat
Mortalitat
Fum
Tabac
Càncer
Consum de tabac
Afeccions cardiovasculars
Afeccions respiratòries
Tabaquismo
Morbilidad
Mortalidad
Humo
Tabaco
Cáncer
Consumo de tabaco
Afecciones cardiovasculares
Afecciones respiratorias
Smoking
Morbidity
Mortality
Smoke
Tobacco
Cancer
Tobacco consumption
Cardiovascular conditions
Respiratory conditions
Pages
5
Publisher
AME Publishing Company
Collection
3; 18
Is part of
Precision Cancer Medicine: a Journal Aiming to Deliver a Lasting Blow to Cancer
Citation
González-Marrón, Adrián; Martín-Sánchez, Juan Carlos; Martínez-Sánchez, Jose M. Current and future perspectives in lung cancer prevention. Precision Cancer Medicine, 2020, 3(18), [p. 1-5]. Disponible en: <https://pcm.amegroups.com/article/view/5724/html>. Fecha de acceso: 10 dic. 2021. DOI: 10.21037/pcm-20-31
This item appears in the following Collection(s)
- Ciències de la Salut [740]
Rights
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Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by-nc-nd/4.0/