Ciències Bàsiques: Recent submissions
Now showing items 61-80 of 98
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The plant noncoding transcriptome: a versatile environmental sensor
(The EMBO Journal, 2023)Plant noncoding RNA transcripts have gained increasing attention in recent years due to growing evidence that they can regulate developmental plasticity. In this review article, we comprehensively analyze ... -
Identification of new microRNA-regulated genes by conserved targeting in plant species
(Nucleic Acids Research, 2012)MicroRNAs (miRNAs) are major regulators of gene expression in multicellular organisms. They recognize their targets by sequence complementarity and guide them to cleavage or translational arrest. It is ... -
Multiple RNA recognition patterns during microRNA biogenesis in plants
(Genome Research, 2013)MicroRNAs (miRNAs) derive from longer precursors with fold-back structures. While animal miRNA precursors have homogenous structures, plant precursors comprise a collection of fold-backs with variable ... -
comTAR: a web tool for the prediction and characterization of conserved microRNA targets in plants
(Bioinformatics, 2014)Motivation: MicroRNAs (miRNAs) are major regulators of gene expression in plants and animals. They recognize their target messenger RNAs (mRNAs) by sequence complementarity and guide them to cleavage ... -
Evolutionary footprints reveal insights into plant MicroRNA biogenesis
(The Plant Cell, 2017)MicroRNAs (miRNAs) are endogenous small RNAs that recognize target sequences by base complementarity and play a role in the regulation of target gene expression. They are processed from longer precursor ... -
Skull fractures by glass bottles tested on cadaveric heads
(International Journal of Legal Medicine, 2023)Head trauma is frequently related to the misuse of drinking vessels as weapons. Forensic reports usually evaluate these blunt injuries as having occurred in scenarios where the alcohol intake is high. ... -
Engineering a genome reduced bacterium to eliminate Staphylococcus aureus biofilms in vivo
(Molecular Systems Biology, 2021)Bacteria present a promising delivery system for treating human diseases. Here, we engineered the genome-reduced human lung pathogen Mycoplasma pneumoniae as a live biotherapeutic to treat biofilm-associated ... -
Modeling cell adhesion and proliferation: a cellular-automata based approach
(Advanced Modeling and Simulation in Engineering Sciences, 2015)Background: Cell adhesion is a process that involves the interaction between the cell membrane and another surface, either a cell or a substrate. Unlike experimental tests, computer models can simulate ... -
Influence of bone-level dental implants placement and of cortical thickness on osseointegration: in silico and in vivo analyses
(Journal of Clinical Medicine, 2022)The purpose of this research is to study the biomechanical response of dental implants in bone-level type locations, 0.5 mm above and below the bone level. In addition, the influence of the thickness ... -
A simplified scheme for piezoelectric anisotropic analysis in human vertebrae using integral methods
(Mathematical Problems in Engineering, 2018)This paper outlines a computational model for the analysis of the piezoelectric behaviour of the vertebral body remodelling process. Particular attention is paid to the algorithms for the simulation of ... -
Simplified qualitative discrete numerical model to determine cracking pattern in brittle materials by means of finite element method
(Mathematical Problems in Engineering, 2017)This paper presents the formulation, implementation, and validation of a simplified qualitative model to determine the crack path of solids considering static loads, infinitesimal strain, and plane ... -
Improved dynamical particle swarm optimization method for structural dynamics
(Mathematical Problems in Engineering, 2019)A methodology to the multiobjective structural design of buildings based on an improved particle swarm optimization algorithm is presented, which has proved to be very efficient and robust in nonlinear ... -
Application of percutaneous needle electrolysis does not elicit temperature changes: an in vitro cadaveric study
(International Journal of Environmental Reseacrh and Public Health, 2022)Percutaneous needle electrolysis (PNE) consists of the ultrasound-guided application of a galvanic electrical current through a solid filament needle. One proposed therapeutic mechanism for this ... -
The ADP-ribose hydrolase NUDT5 is important for DNA repair
(Cell Reports, 2022-12)DNA damage leads to rapid synthesis of poly(ADP-ribose) (pADPr), which is important for damage signaling and repair. pADPr chains are removed by poly(ADP-ribose) glycohydrolase (PARG), releasing free ... -
Engineered live bacteria suppress Pseudomonas aeruginosa infection in mouse lung and dissolve endotracheal-tube biofilms
(Nature Biotechnology, 2023)Engineered live bacteria could provide a new modality for treating lung infections, a major cause of mortality worldwide. In the present study, we engineered a genome-reduced human lung bacterium, ... -
Rationally designed azobenzene photoswitches for efficient two-photon neuronal excitation
(Nature Communications, 2019)Manipulation of neuronal activity using two-photon excitation of azobenzene photoswitches with near-infrared light has been recently demonstrated, but their practical use in neuronal tissue to photostimulate ... -
Regulation of actin dynamics during structural plasticity of dendritic spines: signaling messengers and actin-binding proteins
(Molecular and Cellular Neuroscience, 2018-09)Activity-dependent plasticity of synaptic structure and function plays an essential role in neuronal development and in cognitive functions including learning and memory. The formation, maintenance and ... -
Effectiveness of a multicomponent training program on physical performance and muscle quality in older adults: a quasi-experimental study
(International Journal of Environmental Research and Public Health, 2023)Aging is associated with a decrease in functional capacity, manifested by a loss of strength, physical performance and muscle quality. Multicomponent training (MCT), characterized by the combination of ... -
Study on balance and postural control sccording to the stabilometry in indoor skydivers: a cross-sectional study
(International Journal of Environmental Research and Public Health, 2023)Background: The wind tunnel is a compression cabin through which a stream of air rises homogeneously, generated by fans. To perform different acrobatics, indoor skydivers have to change their body ... -
SURE editing: combining oligo-recombineering and programmable insertion/deletion of selection markers to efficiently edit the Mycoplasma pneumoniae genome
(Nucleic Acids Research, 2022)The development of advanced genetic tools is boosting microbial engineering which can potentially tackle wide-ranging challenges currently faced by our society. Here we present SURE editing, a ...