Ciències Bàsiques: Agregados recientemente
Mostrando ítems 41-60 de 94
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Single-molecule stochastic resonance
(Physical Review X, 2012)Stochastic resonance (SR) is a well-known phenomenon in dynamical systems. It consists of the amplification and optimization of the response of a system assisted by stochastic (random or probabilistic) ... -
Counter-propagating dual-trap optical tweezers based on linear momentum conservation
(Review of Scientific Instruments, 2013)We present a dual-trap optical tweezers setup which directly measures forces using linear momentum conservation. The setup uses a counter-propagating geometry, which allows momentum measurement on each ... -
Derivation of nearest-neighbor DNA parameters in magnesium from single molecule experiments
(Nucleic Acids Research, 2017)DNA hybridization is an essential molecular reaction in biology with many applications. The nearest-neighbor (NN) model for nucleic acids predicts DNA thermodynamics using energy values for the different ... -
Chronic full-band recordings with graphene microtransistors as neural interfaces for discrimination of brain states
(Nanoscale Horizons, 2024)Brain states such as sleep, anesthesia, wakefulness, or coma are characterized by specific patterns of cortical activity dynamics, from local circuits to full-brain emergent properties. We previously ... -
National cultural dimensions and their impact on construction project management in developing countries: the case of Ghana
(Journal of Construction in Developing Countries, 2023)Construction project management (CPM) in developing countries (DCs) tends to experience high levels of failure. These failures have been attributed to technical, behavioural and economic factors. However, ... -
CDKN1A/p21 in breast cancer: part of the problem, or part of the solution?
(International Journal of Molecular Sciences, 2023)Cyclin-dependent kinase inhibitor 1A (Cip1/Waf1/CDKN1A/p21) is a well-established protein, primarily recognised for its pivotal role in the cell cycle, where it induces cell cycle arrest by inhibiting ... -
Muscarinic transmission in the basolateral amygdala is necessary for the acquisition of socially transmitted food preferences in rats
(Neurobiology of Learning and Memory, 2009)We examined the involvement of muscarinic receptors in the basolateral amygdala (BLA) in the social transmission of food preference (STFP) learning by assessing the effects of scopolamine (20 μg/side), ... -
Muscarinic receptor blockade in ventral hippocampus and prelimbic cortex impairs memory for socially transmitted food preference
(Hippocampus, 2008)Acetylcholine is involved in learning and memory and, particularly, in olfactory tasks, but reports on its specific role in consolidation processes are somewhat controversial. The present experiment ... -
Effects of muscarinic receptor antagonism in the basolateral amygdala on two-way active avoidance
(Experimental Brain Research, 2011)The aim of the present study was to investigate whether the blockade of muscarinic receptors (mRs) in the basolateral amygdala (BLA), which receives important cholinergic inputs related to avoidance ... -
Differential effects of muscarinic receptor blockade in prelimbic cortex on acquisition and memory formation of an odor-reward task
(Learning Memory, 2007)The present experiments determined the consequences of blocking muscarinic cholinergic receptors of the prelimbic (PL) cortex in the acquisition and retention of an odor-reward associative task. Rats ... -
Efficiency and precision of microRNA biogenesis modes in plants
(Nucleic Acids Research, 2018)Many evolutionarily conserved microRNAs (miRNAs) in plants regulate transcription factors with key functions in development. Hence, mutations in the core components of the miRNA biogenesis machinery ... -
PhylomeDB V5: an expanding repository for genome-wide catalogues of annotated gene phylogenies
(Nucleic Acids Research, 2022)PhylomeDB is a unique knowledge base providing public access to minable and browsable catalogues of pre-computed genome-wide collections of annotated sequences, alignments and phylogenies (i.e. phylomes) ... -
Spatial control of gene expression by miR319-regulated TCP transcription factors in leaf development
(Plant Physiology, 2018)The characteristic leaf shapes we see in all plants are in good part the outcome of the combined action of several transcription factor networks that translate into cell division activity during the ... -
Identification of key sequence features required for microRNA biogenesis in plants
(Nature Communications, 2020)MicroRNAs (miRNAs) are endogenous small RNAs of ∼21 nt that regulate multiple biological pathways in multicellular organisms. They derive from longer transcripts that harbor an imperfect stem-loop ... -
MetaPhOrs 2.0: integrative, phylogeny-based inference of orthology and paralogy across the tree of life
(Nucleic Acids Research, 2020)Inferring homology relationships across genes in different species is a central task in comparative genomics. Therefore, a large number of resources and methods have been developed over the years. Some ... -
Structural characterization of NORAD reveals a stabilizing role of spacers and two new repeat units
(Computational and Structural Biotechnology Journal, 2021)Long non-coding RNAs (lncRNAs) can perform a variety of key cellular functions by interacting with proteins and other RNAs. Recent studies have shown that the functions of lncRNAS are largely mediated ... -
The plant noncoding transcriptome: a versatile environmental sensor
(The EMBO Journal, 2023)Plant noncoding RNA transcripts have gained increasing attention in recent years due to growing evidence that they can regulate developmental plasticity. In this review article, we comprehensively analyze ... -
Identification of new microRNA-regulated genes by conserved targeting in plant species
(Nucleic Acids Research, 2012)MicroRNAs (miRNAs) are major regulators of gene expression in multicellular organisms. They recognize their targets by sequence complementarity and guide them to cleavage or translational arrest. It is ... -
Multiple RNA recognition patterns during microRNA biogenesis in plants
(Genome Research, 2013)MicroRNAs (miRNAs) derive from longer precursors with fold-back structures. While animal miRNA precursors have homogenous structures, plant precursors comprise a collection of fold-backs with variable ... -
comTAR: a web tool for the prediction and characterization of conserved microRNA targets in plants
(Bioinformatics, 2014)Motivation: MicroRNAs (miRNAs) are major regulators of gene expression in plants and animals. They recognize their target messenger RNAs (mRNAs) by sequence complementarity and guide them to cleavage ...